spironolactone has been researched along with Brain Diseases in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mulatero, P | 1 |
| Milan, A | 1 |
| Williams, TA | 1 |
| Veglio, F | 1 |
| Andler, W | 1 |
| Roosen, K | 1 |
| Reinhardt, V | 1 |
1 review available for spironolactone and Brain Diseases
| Article | Year |
|---|---|
Mineralocorticoid receptor blockade in the protection of target organ damage.
Topics: Aldosterone; Animals; Brain; Brain Diseases; Cardiovascular Diseases; Eplerenone; Heart; Humans; Hyp | 2006 |
2 other studies available for spironolactone and Brain Diseases
| Article | Year |
|---|---|
[Hypothalamic hyperosmolarity in childhood (author's transl)].
Topics: Astrocytoma; Brain Diseases; Brain Neoplasms; Child; Craniopharyngioma; Female; Histiocytosis, Lange | 1979 |
[Soludactone and neurosurgical recovery].
Topics: Adrenal Cortex Hormones; Blood Gas Analysis; Brain Diseases; Brain Edema; Brain Injuries; Brain Neop | 1974 |