spironolactone has been researched along with Bradycardia in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)." | 9.04 | [Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978) |
| "In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)." | 5.04 | [Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez Casal, V | 1 |
| Lage Cendon, L | 1 |
| Lago Preciado, G | 1 |
| Vara Adrio, S | 1 |
| Isabel, J | 1 |
| Champion, JC | 1 |
| Muratani, H | 1 |
| Kawasaki, T | 1 |
| Omae, T | 1 |
| Ebel, H | 1 |
| Lübke, H | 1 |
| Klaus, D | 1 |
| Zehner, J | 1 |
| Witzgall, H | 1 |
| Thind, GS | 1 |
| Blakemore, WS | 1 |
| Zinsser, HF | 1 |
1 trial available for spironolactone and Bradycardia
| Article | Year |
|---|---|
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydroch | 1978 |
4 other studies available for spironolactone and Bradycardia
| Article | Year |
|---|---|
[Ivabradine poisoning with suicide intention].
Topics: Adult; Antidotes; Benzazepines; Bradycardia; Calcium Gluconate; Combined Modality Therapy; Drug Over | 2015 |
Junctional escape rhythm secondary to acute hyperkalemic renal failure in the setting of concurrent beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradycardia; Diuretics; | 2006 |
A possible role of hypokalemia in the manifestation of high QRS voltage and sinus bradycardia in patients with primary aldosteronism.
Topics: Adult; Blood Pressure; Bradycardia; Electrocardiography; Female; Humans; Hyperaldosteronism; Hyperte | 1984 |
Direct current cardioversion in digitalized patients with mitral valve disease.
Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Cardiac Complexes, Pr | 1969 |