spironolactone has been researched along with Bone Fractures in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine whether spironolactone use is associated with fractures in men with congestive heart failure (CHF)." | 7.74 | Fracture risk in men with congestive heart failure risk reduction with spironolactone. ( Ahmad, K; Bush, AJ; Carbone, LD; Chishti, WA; Cho, T; Cross, JD; Dhawan, S; Dishmon, DA; Gupta, M; Hajjar, MA; Haskin, AR; Khan, BQ; Khan, M; Khouzam, RN; Nasser, W; Nesheiwat, JP; Raza, SH; Sepanski, RJ; Weber, KT; Womack, CR, 2008) |
| "The purpose of this study was to determine whether spironolactone use is associated with fractures in men with congestive heart failure (CHF)." | 3.74 | Fracture risk in men with congestive heart failure risk reduction with spironolactone. ( Ahmad, K; Bush, AJ; Carbone, LD; Chishti, WA; Cho, T; Cross, JD; Dhawan, S; Dishmon, DA; Gupta, M; Hajjar, MA; Haskin, AR; Khan, BQ; Khan, M; Khouzam, RN; Nasser, W; Nesheiwat, JP; Raza, SH; Sepanski, RJ; Weber, KT; Womack, CR, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carbone, LD | 1 |
| Cross, JD | 1 |
| Raza, SH | 1 |
| Bush, AJ | 1 |
| Sepanski, RJ | 1 |
| Dhawan, S | 1 |
| Khan, BQ | 1 |
| Gupta, M | 1 |
| Ahmad, K | 1 |
| Khouzam, RN | 1 |
| Dishmon, DA | 1 |
| Nesheiwat, JP | 1 |
| Hajjar, MA | 1 |
| Chishti, WA | 1 |
| Nasser, W | 1 |
| Khan, M | 1 |
| Womack, CR | 1 |
| Cho, T | 1 |
| Haskin, AR | 1 |
| Weber, KT | 1 |
| Vallent, K | 1 |
| Mundi, B | 1 |
| Perner, F | 1 |
| Nuding, J | 1 |
2 other studies available for spironolactone and Bone Fractures
| Article | Year |
|---|---|
Fracture risk in men with congestive heart failure risk reduction with spironolactone.
Topics: Aged; Fractures, Bone; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagoni | 2008 |
[On the effect of heparin and corticoid therapy on the number of circulating eosinophils].
Topics: Adrenocorticotropic Hormone; Aldosterone; Cortisone; Depression, Chemical; Desoxycorticosterone; Eos | 1966 |