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spironolactone and Bone Diseases

spironolactone has been researched along with Bone Diseases in 3 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Bone Diseases: Diseases of BONES.

Research Excerpts

ExcerptRelevanceReference
" Hyperaldosteronism due to klotho deficiency results in vascular calcification, which can be mitigated by spironolactone treatment."4.90Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease. ( Fahrleitner-Pammer, A; Gaksch, M; Grübler, M; Kienreich, K; Kraigher-Krainer, E; März, W; Mrak, P; Pieske, B; Pilz, S; Ritz, E; Rus-Machan, J; Tomaschitz, A; Toplak, H; Verheyen, N, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tomaschitz, A1
Ritz, E1
Pieske, B1
Rus-Machan, J1
Kienreich, K1
Verheyen, N1
Gaksch, M1
Grübler, M1
Fahrleitner-Pammer, A1
Mrak, P1
Toplak, H1
Kraigher-Krainer, E1
März, W1
Pilz, S1
Arant, BS1
Brackett, NC1
Young, RB1
Still, WJ1
Tuchweber, B1
Garg, BD1
Hatakeyama, S1

Reviews

1 review available for spironolactone and Bone Diseases

ArticleYear
Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease.
    Metabolism: clinical and experimental, 2014, Volume: 63, Issue:1

    Topics: Adrenalectomy; Aldosterone; Animals; Bone Density; Bone Diseases; Calcium; Cardiovascular Diseases;

2014

Other Studies

2 other studies available for spironolactone and Bone Diseases

ArticleYear
Case studies of siblings with juxtaglomerular hyperplasia and secondary aldosteronism associated with severe azotemia and renal rickets--Bartter's syndrome or disease?
    Pediatrics, 1970, Volume: 46, Issue:3

    Topics: Aldosterone; Alkalosis; Angiotensin II; Bone Diseases; Child; Child, Preschool; Humans; Hyperaldoste

1970
Prevention of hypervitaminosis A by spironolactone and anabolic steroids.
    Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1970, Volume: 40, Issue:5

    Topics: Absorption; Anabolic Agents; Animals; Bone and Bones; Bone Diseases; Desoxycorticosterone; Drug Anta

1970