spironolactone has been researched along with Bone Diseases, Metabolic in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Bone Diseases, Metabolic: Diseases that affect the METABOLIC PROCESSES of BONE TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For the first time neonatal variant of Bartter syndrome to 14." | 2.42 | [Bartter syndrome and it's neonatal type]. ( Jakutovic, M; Jankauskiene, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fumoto, T | 1 |
| Ishii, KA | 1 |
| Ito, M | 1 |
| Berger, S | 1 |
| Schütz, G | 1 |
| Ikeda, K | 1 |
| Jankauskiene, A | 1 |
| Jakutovic, M | 1 |
| Atkinson, SA | 1 |
| Shah, JK | 1 |
| McGee, C | 1 |
| Steele, BT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Calciuric Effect and Cyclic Parenteral Nutrition in Preterm Infants[NCT00711763] | 1 participants (Actual) | Observational | 2008-07-31 | Terminated (stopped due to failure to recruit more patients and lack of supporting personnel.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for spironolactone and Bone Diseases, Metabolic
| Article | Year |
|---|---|
[Bartter syndrome and it's neonatal type].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Bone Diseases, Metabolic; Cal | 2003 |
2 other studies available for spironolactone and Bone Diseases, Metabolic
| Article | Year |
|---|---|
Mineralocorticoid receptor function in bone metabolism and its role in glucocorticoid-induced osteopenia.
Topics: Animals; Bone and Bones; Bone Diseases, Metabolic; Eplerenone; Glucocorticoids; Mice; Mice, Inbred S | 2014 |
Mineral excretion in premature infants receiving various diuretic therapies.
Topics: Birth Weight; Bone Diseases, Metabolic; Diuretics; Drug Therapy, Combination; Female; Furosemide; Hu | 1988 |