Page last updated: 2024-11-07

spironolactone and Bleeding

spironolactone has been researched along with Bleeding in 12 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Research Excerpts

ExcerptRelevanceReference
"It is a case report of bleeding when using dabigatran in patient with renal failure caused by the concurrent use of spironolactone and angiotensin-converting enzyme (ACE) inhibitors."7.79[Bleeding in the appointment of dabigatran in the patients with renal insufficiency caused by coadministration of spironolactone and ACE inhibitors]. ( Andreev, DA; Gappoeva, ZK; Giliarov, MIu; Sychev, DA, 2013)
"It is a case report of bleeding when using dabigatran in patient with renal failure caused by the concurrent use of spironolactone and angiotensin-converting enzyme (ACE) inhibitors."3.79[Bleeding in the appointment of dabigatran in the patients with renal insufficiency caused by coadministration of spironolactone and ACE inhibitors]. ( Andreev, DA; Gappoeva, ZK; Giliarov, MIu; Sychev, DA, 2013)
"Ascites, variceal bleeding, hepatic encephalopathy, and hepatorenal syndrome are among the complications you are likely to encounter when caring for a patient with cirrhosis."1.42Cirrhosis complications: keeping them under control. ( Eliacin, I; Kashan, S; Minor, SE; Whisenant, EB, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andreev, DA1
Gappoeva, ZK1
Sychev, DA1
Giliarov, MIu1
Minor, SE1
Eliacin, I1
Kashan, S1
Whisenant, EB1
Autret-Leca, E1
Abecasis, R1
Kravetz, D1
Fassio, E1
Ameigeiras, B1
Garcia, D1
Isla, R1
Landeira, G1
Dominguez, N1
Romero, G1
Argonz, J1
Terg, R1
MCNEILL, IF1
DIXON, JP1
MOORE, FD1
CHAPIS, NJ1
Schumpelick, V1
Hrynyschyn, K1
Kortmann, KB1
Ogata, E1
Nishiki, K1
Kugai, N1
Kishikawa, T1
Selye, H1
Szabo, S3
Lazar, G2
Husztik, E1
Kovacs, K1
Somogyi, A1

Trials

1 trial available for spironolactone and Bleeding

ArticleYear
Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: A preliminary study.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Double-Blind Method; Drug Therapy, Combination; Esophageal and Ga

2003

Other Studies

11 other studies available for spironolactone and Bleeding

ArticleYear
[Bleeding in the appointment of dabigatran in the patients with renal insufficiency caused by coadministration of spironolactone and ACE inhibitors].
    Kardiologiia, 2013, Volume: 53, Issue:3

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Atrial Fibrillation; Benzimidazoles; beta-Alanine; C

2013
Cirrhosis complications: keeping them under control.
    The Journal of family practice, 2015, Volume: 64, Issue:6

    Topics: Antihypertensive Agents; Ascites; Diuretics; Furosemide; Hemorrhage; Hepatic Encephalopathy; Humans;

2015
[Drugs news].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16, Issue:5

    Topics: Acetaminophen; Acupuncture; Asthma; Child; Glucocorticoids; Hemorrhage; Humans; Placebo Effect; Resp

2009
THE EFFECTS OF HEMORRHAGE AND HORMONES ON THE PARTITION OF BODY WATER. III. THE EFFECTS OF HEMORRHAGE AND CORTICOSTEROIDS ON FLUID PARTITION IN THE ADRENALECTOMIZED DOG.
    The Journal of surgical research, 1963, Volume: 3

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Blood Pressure; Blood Volume; Body Fluids; Body

1963
PORTACAVAL SHUNT PERFORMED DURING PREGNANCY.
    American journal of obstetrics and gynecology, 1964, Sep-15, Volume: 90

    Topics: Chlorothiazide; Diet, Sodium-Restricted; Esophageal and Gastric Varices; Female; Gastrointestinal He

1964
[Therapy of ascites by peritoneo-venous shunt].
    Deutsche medizinische Wochenschrift (1946), 1984, Jun-15, Volume: 109, Issue:24

    Topics: Ascites; Diet, Sodium-Restricted; Equipment Failure; Furosemide; Hemorrhage; Humans; Life Expectancy

1984
Oxidative response to aldosterone of pyridine nucleotide in rat kidney in situ.
    The American journal of physiology, 1977, Volume: 232, Issue:4

    Topics: Adenine Nucleotides; Aldosterone; Animals; Calcitonin; Cycloheximide; Dactinomycin; Desoxycorticoste

1977
Protection by various catatoxic steroids and estradiol against the fatal hemorrhagic syndrome produced by bishydroxycoumarin in the rat.
    Vox sanguinis, 1972, Volume: 22, Issue:3

    Topics: Animals; Castration; Dicumarol; Estradiol; Female; Hemorrhage; Oxandrolone; Rats; Spironolactone; St

1972
The experimental production of hemorrhagic lesions in the rat adrenal, liver and lung by basic polyglutamic acid derivatives.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1972, Volume: 159, Issue:1

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Chemical and Drug Induced Liver Injury; Ethylestren

1972
Effect of hypophysectomy and catatoxic steroids on thioacetamide-induced adrenal lesions in rats.
    Endokrinologie, 1973, Volume: 61, Issue:1

    Topics: Acetamides; Adrenal Gland Diseases; Adrenal Glands; Anabolic Agents; Animals; Dexamethasone; Ethyles

1973
Prevention by spironolactone of 7,12-dimethylbenz(a)anthracene-induced adrenal necrosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:4

    Topics: Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Female; Hemorrhage; Necrosis; Rats; Spironolact

1969