spironolactone has been researched along with Bleeding Between Periods in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate and compare the effects of spironolactone and spironolactone plus metformin treatments on body mass index (BMI), hirsutism score, hormone levels, and insulin resistance in women with polycystic ovary syndrome (PCOS)." | 9.22 | Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome. ( Acmaz, B; Diri, H; Karaburgu, S; Karaca, Z; Kelestimur, F; Tanriverdi, F; Unluhizarci, K, 2016) |
| "Spironolactone (SP) is an effective treatment for polycystic ovary syndrome (PCOS), but it is often associated with menstrual abnormalities whose mechanism is still under investigation." | 7.83 | Spironolactone and intermenstrual bleeding in polycystic ovary syndrome with normal BMI. ( Ambrosini, G; Andrisani, A; Armanini, D; Bordin, L; Boscaro, M; Donà, G; Ragazzi, E; Sabbadin, C; Zermiani, M, 2016) |
| "The aim of this study was to evaluate and compare the effects of spironolactone and spironolactone plus metformin treatments on body mass index (BMI), hirsutism score, hormone levels, and insulin resistance in women with polycystic ovary syndrome (PCOS)." | 5.22 | Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome. ( Acmaz, B; Diri, H; Karaburgu, S; Karaca, Z; Kelestimur, F; Tanriverdi, F; Unluhizarci, K, 2016) |
| "Spironolactone (SP) is an effective treatment for polycystic ovary syndrome (PCOS), but it is often associated with menstrual abnormalities whose mechanism is still under investigation." | 3.83 | Spironolactone and intermenstrual bleeding in polycystic ovary syndrome with normal BMI. ( Ambrosini, G; Andrisani, A; Armanini, D; Bordin, L; Boscaro, M; Donà, G; Ragazzi, E; Sabbadin, C; Zermiani, M, 2016) |
| "We followed up a girl with primary aldosteronism for 8 y, which was diagnosed at 6 y of age when she was referred to us for evaluation of heart murmur and growth failure." | 1.33 | Long-term follow-up of a girl with primary aldosteronism: effect of potassium supplement. ( Higashino, H; Hirose, Y; Isozaki, Y; Kobayashi, Y; Noda, Y; Takaya, J, 2005) |
| " In 11 women (68%), the dosage had to be decreased or the medication discontinued due to side-effects." | 1.27 | Side-effects of spironolactone therapy in the hirsute woman. ( Helfer, EL; Miller, JL; Rose, LI, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diri, H | 1 |
| Karaburgu, S | 1 |
| Acmaz, B | 1 |
| Unluhizarci, K | 1 |
| Tanriverdi, F | 1 |
| Karaca, Z | 1 |
| Kelestimur, F | 1 |
| Sabbadin, C | 1 |
| Andrisani, A | 1 |
| Zermiani, M | 1 |
| Donà, G | 1 |
| Bordin, L | 1 |
| Ragazzi, E | 1 |
| Boscaro, M | 1 |
| Ambrosini, G | 1 |
| Armanini, D | 1 |
| Takaya, J | 1 |
| Isozaki, Y | 1 |
| Hirose, Y | 1 |
| Higashino, H | 1 |
| Noda, Y | 1 |
| Kobayashi, Y | 1 |
| Danĕková, H | 1 |
| Tison, P | 1 |
| Helfer, EL | 1 |
| Miller, JL | 1 |
| Rose, LI | 1 |
1 trial available for spironolactone and Bleeding Between Periods
| Article | Year |
|---|---|
Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Dehydroepiandrosterone Sulfate; Drug Therapy, Com | 2016 |
4 other studies available for spironolactone and Bleeding Between Periods
| Article | Year |
|---|---|
Spironolactone and intermenstrual bleeding in polycystic ovary syndrome with normal BMI.
Topics: Adult; Body Mass Index; Female; Humans; Menstrual Cycle; Metrorrhagia; Mineralocorticoid Receptor An | 2016 |
Long-term follow-up of a girl with primary aldosteronism: effect of potassium supplement.
Topics: Adolescent; Blood Pressure; Body Height; Body Weight; Child; Child Development; Developmental Disabi | 2005 |
[Metrorrhagia on aldadien with butocin administration].
Topics: Drug Combinations; Female; Humans; Menopause; Metrorrhagia; Middle Aged; Spironolactone; Thiazines | 1976 |
Side-effects of spironolactone therapy in the hirsute woman.
Topics: Adult; Alopecia; Female; Hirsutism; Humans; Menstrual Cycle; Metrorrhagia; Spironolactone; Testoster | 1988 |