spironolactone has been researched along with Autistic Disorder in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone is an aldosterone antagonist and potassium-sparing diuretic with a desirable safety profile." | 5.34 | Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders. ( Bradstreet, JJ; El-Dahr, JM; Granpeesheh, D; Rossignol, D; Smith, S, 2007) |
| "Spironolactone is an aldosterone antagonist and potassium-sparing diuretic with a desirable safety profile." | 1.34 | Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders. ( Bradstreet, JJ; El-Dahr, JM; Granpeesheh, D; Rossignol, D; Smith, S, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradstreet, JJ | 1 |
| Smith, S | 1 |
| Granpeesheh, D | 1 |
| El-Dahr, JM | 1 |
| Rossignol, D | 1 |
1 other study available for spironolactone and Autistic Disorder
| Article | Year |
|---|---|
Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders.
Topics: Androgen Antagonists; Autistic Disorder; Child; Humans; Mineralocorticoid Receptor Antagonists; Mode | 2007 |