spironolactone has been researched along with Arthritis, Gouty in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Arthritis, Gouty: Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular. Acute and chronic gouty arthritis are associated with accumulation of MONOSODIUM URATE in and around affected joints.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone use was associated with a decreased occurrence of gouty arthritis (OR 0." | 1.38 | A case-control study of determinants for the occurrence of gouty arthritis in heart failure patients. ( Hueskes, BA; Janssen, M; Janssens, HJ; Leen, AC; Mantel-Teeuwisse, AK; Ninaber, PA; Roovers, EA; van de Lisdonk, EH; Westra, R; Willems, FF, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hueskes, BA | 1 |
| Willems, FF | 1 |
| Leen, AC | 1 |
| Ninaber, PA | 1 |
| Westra, R | 1 |
| Mantel-Teeuwisse, AK | 1 |
| Janssens, HJ | 1 |
| van de Lisdonk, EH | 1 |
| Roovers, EA | 1 |
| Janssen, M | 1 |
1 other study available for spironolactone and Arthritis, Gouty
| Article | Year |
|---|---|
A case-control study of determinants for the occurrence of gouty arthritis in heart failure patients.
Topics: Aged; Antihypertensive Agents; Arthritis, Gouty; Case-Control Studies; Confidence Intervals; Female; | 2012 |