spironolactone has been researched along with Apparent Mineralocorticoid Excess Syndrome in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone was initiated." | 1.72 | Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child. ( Baltu, D; Çelik Ertaş, NB; Duzova, A; Gönç, N; Gulhan, B; Ozcan, HN; Özdemir, G; Ünsal, Y; Utine, E, 2022) |
| "Spironolactone treatment resulted in decreased blood pressure and rise in serum potassium levels." | 1.46 | Apparent mineralocorticoid excess and the long term treatment of genetic hypertension. ( Khattab, A; New, MI; Razzaghy-Azar, M; Yau, M, 2017) |
| "Hypertension is attributed to sodium retention in the distal nephron, but 11βHSD2 is also expressed in the brain." | 1.43 | Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension. ( Al-Dujaili, EA; Bailey, MA; Christensen, TH; Evans, LC; Holmes, MC; Ivy, JR; Kenyon, CJ; McNairn, JA; Menzies, RI; Mullins, JJ; Seckl, JR; Wyrwoll, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Gulhan, B | 1 |
| Ünsal, Y | 1 |
| Baltu, D | 1 |
| Çelik Ertaş, NB | 1 |
| Özdemir, G | 1 |
| Utine, E | 1 |
| Ozcan, HN | 1 |
| Duzova, A | 1 |
| Gönç, N | 1 |
| Kucuk, N | 1 |
| Yavas Abalı, Z | 1 |
| Abalı, S | 1 |
| Canpolat, N | 1 |
| Yesil, G | 1 |
| Turan, S | 1 |
| Bereket, A | 1 |
| Guran, T | 1 |
| Razzaghy-Azar, M | 1 |
| Yau, M | 1 |
| Khattab, A | 1 |
| New, MI | 1 |
| Evans, LC | 1 |
| Ivy, JR | 1 |
| Wyrwoll, C | 1 |
| McNairn, JA | 1 |
| Menzies, RI | 1 |
| Christensen, TH | 1 |
| Al-Dujaili, EA | 1 |
| Kenyon, CJ | 1 |
| Mullins, JJ | 1 |
| Seckl, JR | 1 |
| Holmes, MC | 1 |
| Bailey, MA | 1 |
| Al-Harbi, T | 1 |
| Al-Shaikh, A | 1 |
| Woodhouse, NJ | 1 |
| Elshafie, OT | 1 |
| Mehar, A | 1 |
| Johnston, WJ | 1 |
| Al-Kaabi, JM | 1 |
| Mune, T | 1 |
1 review available for spironolactone and Apparent Mineralocorticoid Excess Syndrome
| Article | Year |
|---|---|
[Deficiency of 11beta-hydroxysteroid dehydrogenase type 2 (syndrome of apparent mineralocorticoid excess)].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Diagnosis, Differential; Eplerenone; Mineralocorticoid | 2006 |
6 other studies available for spironolactone and Apparent Mineralocorticoid Excess Syndrome
| Article | Year |
|---|---|
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; | 2022 |
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; | 2022 |
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; | 2022 |
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; | 2022 |
A rare cause of hypertension in childhood: Answers.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos | 2020 |
A rare cause of hypertension in childhood: Answers.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos | 2020 |
A rare cause of hypertension in childhood: Answers.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos | 2020 |
A rare cause of hypertension in childhood: Answers.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos | 2020 |
Apparent mineralocorticoid excess and the long term treatment of genetic hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Blood Pressure; Child; Child, Preschool; D | 2017 |
Apparent mineralocorticoid excess and the long term treatment of genetic hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Blood Pressure; Child; Child, Preschool; D | 2017 |
Apparent mineralocorticoid excess and the long term treatment of genetic hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Blood Pressure; Child; Child, Preschool; D | 2017 |
Apparent mineralocorticoid excess and the long term treatment of genetic hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Blood Pressure; Child; Child, Preschool; D | 2017 |
Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Baroreflex; Corticosterone; Craving; Dexametha | 2016 |
Apparent mineralocorticoid excess syndrome: report of one family with three affected children.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Child; Child, Preschool; Dietary Supplements; DNA | 2012 |
Spironolactone responsive familial hypertension. A potentially high prevalence of mineralocorticoid disease in Oman.
Topics: Adult; Aged; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Excess Syndrome, App | 2003 |