spironolactone has been researched along with Aortic Incompetence in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone treatment decreased the total heart weight." | 1.38 | Effects of spironolactone treatment on an experimental model of chronic aortic valve regurgitation. ( Arsenault, M; Couet, J; Lachance, D; Roussel, E; Zendaoui, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moura, LM | 1 |
| Rocha-Gonçalves, F | 1 |
| Emery, RW | 1 |
| Pai, AD | 1 |
| Pai, RG | 1 |
| Zendaoui, A | 1 |
| Lachance, D | 1 |
| Roussel, E | 1 |
| Couet, J | 1 |
| Arsenault, M | 1 |
| Rühlmann, C | 1 |
| Wittig, K | 1 |
| Koksch, M | 1 |
| Müller, J | 1 |
| Olesen, KH | 1 |
| Valentin, N | 1 |
6 other studies available for spironolactone and Aortic Incompetence
| Article | Year |
|---|---|
Aldosterone antagonists and chronic aortic regurgitation: promising but not quite ready for prime time.
Topics: Animals; Aortic Valve Insufficiency; Cardiomegaly; Male; Mineralocorticoid Receptor Antagonists; Spi | 2012 |
Potentially modifiable biological targets in aortic regurgitation.
Topics: Animals; Aortic Valve Insufficiency; Cardiomegaly; Male; Mineralocorticoid Receptor Antagonists; Spi | 2012 |
Effects of spironolactone treatment on an experimental model of chronic aortic valve regurgitation.
Topics: Animals; Aortic Valve Insufficiency; Blood Pressure; Cardiomegaly; Chronic Disease; Diastole; Diseas | 2012 |
[Aneurysm of the ascending aorta in tertiary syphilis].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antitussive Agents; Aortic Aneurysm, Thoracic; Aortic Valv | 1996 |
Total exchangeable potassium, sodium and chloride in patients with severe valvular heart disease during preparation for cardiac surgery.
Topics: Adult; Aortic Valve Insufficiency; Atrial Fibrillation; Bicarbonates; Blood Proteins; Body Compositi | 1973 |
Heart failure. II.
Topics: Aged; Aortic Valve Insufficiency; Digitoxin; Digoxin; Ethacrynic Acid; Female; Furosemide; Heart Fai | 1971 |