spironolactone has been researched along with Aortic Aneurysm, Thoracic in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The concomitant use of TLV and conventional diuretics is safe and effective for fluid management after TAR using cardiopulmonary bypass, selective cerebral perfusion, and hypothermic circulatory arrest." | 1.51 | Safety and Effectiveness of Tolvaptan Administration after Total Arch Replacement. ( Iida, Y; Shimizu, H; Yoshitake, A, 2019) |
| "Primary hyperaldosteronism is a rare (<1%) and underdiagnosed cause of secondary hypertension." | 1.34 | Is primary hyperaldosteronism a risk factor for aortic dissection? ( Ahmed, SH; Husain, NM; Khawaja, SN; Massey, CV; Pettyjohn, FS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iida, Y | 1 |
| Yoshitake, A | 1 |
| Shimizu, H | 1 |
| Liu, S | 1 |
| Xie, Z | 1 |
| Daugherty, A | 1 |
| Cassis, LA | 1 |
| Pearson, KJ | 1 |
| Gong, MC | 1 |
| Guo, Z | 1 |
| Ahmed, SH | 1 |
| Husain, NM | 1 |
| Khawaja, SN | 1 |
| Massey, CV | 1 |
| Pettyjohn, FS | 1 |
| Rühlmann, C | 1 |
| Wittig, K | 1 |
| Koksch, M | 1 |
| Müller, J | 1 |
4 other studies available for spironolactone and Aortic Aneurysm, Thoracic
| Article | Year |
|---|---|
Safety and Effectiveness of Tolvaptan Administration after Total Arch Replacement.
Topics: Administration, Oral; Aged; Antidiuretic Hormone Receptor Antagonists; Aortic Aneurysm, Thoracic; Bl | 2019 |
Mineralocorticoid receptor agonists induce mouse aortic aneurysm formation and rupture in the presence of high salt.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2013 |
Is primary hyperaldosteronism a risk factor for aortic dissection?
Topics: Antihypertensive Agents; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortography; Cardiac Catheter | 2007 |
[Aneurysm of the ascending aorta in tertiary syphilis].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antitussive Agents; Aortic Aneurysm, Thoracic; Aortic Valv | 1996 |