spironolactone has been researched along with Anti-GBM Disease in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice receiving eplerenone showed significantly decreased albuminuria and glomerular sclerosis at day 7 and 14 after induction of anti-GBM GN." | 3.77 | The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis. ( Eller, K; Huber, JM; Kirsch, AH; Mayer, G; Rosenkranz, AR; Tagwerker, A; Zitt, E, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zitt, E | 1 |
| Eller, K | 1 |
| Huber, JM | 1 |
| Kirsch, AH | 1 |
| Tagwerker, A | 1 |
| Mayer, G | 1 |
| Rosenkranz, AR | 1 |
1 other study available for spironolactone and Anti-GBM Disease
| Article | Year |
|---|---|
The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis.
Topics: Albuminuria; Animals; Anti-Glomerular Basement Membrane Disease; CD4-Positive T-Lymphocytes; CD8-Pos | 2011 |