spironolactone has been researched along with Angina at Rest in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The Eplerenone Neurohormonal Efficacy and Survival Study (EPHESUS) with eplerenone in patients who were post-myocardial infarction underscores the additive benefit of such a strategy in post-infarction patients that typify an at-risk population for recurrent cardiovascular events." | 8.82 | Eplerenone: will it have a role in the treatment of acute coronary syndromes? ( Meier, DJ; Pitt, B; Rajagopalan, S, 2004) |
| " The Eplerenone Neurohormonal Efficacy and Survival Study (EPHESUS) with eplerenone in patients who were post-myocardial infarction underscores the additive benefit of such a strategy in post-infarction patients that typify an at-risk population for recurrent cardiovascular events." | 4.82 | Eplerenone: will it have a role in the treatment of acute coronary syndromes? ( Meier, DJ; Pitt, B; Rajagopalan, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mihailidou, AS | 1 |
| Loan Le, TY | 1 |
| Mardini, M | 1 |
| Funder, JW | 1 |
| Meier, DJ | 1 |
| Pitt, B | 1 |
| Rajagopalan, S | 1 |
1 review available for spironolactone and Angina at Rest
| Article | Year |
|---|---|
Eplerenone: will it have a role in the treatment of acute coronary syndromes?
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Collagen; Coronary Restenosis; Eplerenone; Humans; | 2004 |
1 other study available for spironolactone and Angina at Rest
| Article | Year |
|---|---|
Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction.
Topics: Aldosterone; Angina, Unstable; Animals; Apoptosis; Dexamethasone; Glucocorticoids; Hormone Antagonis | 2009 |