spironolactone has been researched along with Aneurysm, Ruptured in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of the 82 patients, 80 (88 unruptured aneurysms) were followed for a mean of 21." | 2.87 | Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study. ( Abe, T; Harada, M; Kanematsu, Y; Kinouchi, T; Kitazato, KT; Korai, M; Kuwayama, K; Matsushita, N; Miyamoto, T; Mure, H; Nagahiro, S; Nakajima, K; Okayama, Y; Satomi, J; Shimada, K; Tada, Y; Yagi, K; Yamaguchi, T, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagahiro, S | 1 |
| Tada, Y | 1 |
| Satomi, J | 1 |
| Kinouchi, T | 1 |
| Kuwayama, K | 1 |
| Yagi, K | 1 |
| Nakajima, K | 1 |
| Matsushita, N | 1 |
| Miyamoto, T | 1 |
| Yamaguchi, T | 1 |
| Shimada, K | 1 |
| Korai, M | 1 |
| Mure, H | 1 |
| Okayama, Y | 1 |
| Abe, T | 1 |
| Harada, M | 1 |
| Kitazato, KT | 1 |
| Kanematsu, Y | 1 |
1 trial available for spironolactone and Aneurysm, Ruptured
| Article | Year |
|---|---|
Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study.
Topics: Aged; Aneurysm, Ruptured; Brain; Disease Progression; Eplerenone; Female; Follow-Up Studies; Humans; | 2018 |