Page last updated: 2024-11-07

spironolactone and Anesthesia

spironolactone has been researched along with Anesthesia in 4 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, SA1
Dutia, MB1
Uchida, T1
Ohtaki, Y1
Kido, H1
Watanabe, M1
Selye, H1
Solymoss, B1
Krajny, M1
Varga, S1
Werringloer, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prednisone Treatment for Vestibular Neuronitis[NCT00271791]Phase 217 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for spironolactone and Anesthesia

ArticleYear
Lesion-induced plasticity in rat vestibular nucleus neurones dependent on glucocorticoid receptor activation.
    The Journal of physiology, 1999, Jul-01, Volume: 518, Issue:Pt 1

    Topics: Anesthesia; Animals; Behavior, Animal; Denervation; Dexamethasone; Ear, Inner; Glucocorticoids; Immu

1999
Diuretic profile of a novel loop diuretic torasemide in rats and dogs.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:6

    Topics: Anesthesia; Animals; Diuretics; Dogs; Drug Therapy, Combination; Female; Male; Rats; Rats, Inbred St

1991
Protection against methyprylon overdosage by catatoxic steroids.
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:2

    Topics: Anabolic Agents; Anesthesia; Animals; Desoxycorticosterone; Ethylestrenol; Female; Hypnotics and Sed

1970
Suppression by nucleic acid- and protein-synthesis inhibitors of drug detoxication induced by spironolactone or ethylestrenol.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:3

    Topics: Anesthesia; Animals; Antimetabolites; Chloramphenicol; Cycloheximide; Dactinomycin; Ethylestrenol; F

1970