spironolactone has been researched along with Amenorrhea in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Amenorrhea: Absence of menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical and endocrine evaluations of 39 patients with hirsutism were performed to determine the effectiveness and site(s) of action of an antiandrogenic compound, spironolactone." | 7.66 | Treatment of hirsutism with spironolactone. ( Cumming, DC; Rebar, RW; Yang, JC; Yen, SS, 1982) |
| "Clinical and endocrine evaluations of 39 patients with hirsutism were performed to determine the effectiveness and site(s) of action of an antiandrogenic compound, spironolactone." | 3.66 | Treatment of hirsutism with spironolactone. ( Cumming, DC; Rebar, RW; Yang, JC; Yen, SS, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cumming, DC | 1 |
| Yang, JC | 1 |
| Rebar, RW | 1 |
| Yen, SS | 1 |
| Potter, C | 1 |
| Willis, D | 1 |
| Sharp, HL | 1 |
| Scharzenberg, SJ | 1 |
| Siegberg, R | 1 |
| Ylöstalo, P | 1 |
| Laatikainen, T | 1 |
| Pelkonen, R | 1 |
| Stenman, UH | 1 |
| Levitt, JI | 1 |
1 trial available for spironolactone and Amenorrhea
| Article | Year |
|---|---|
Endocrine and clinical effects of spironolactone in female hyperandrogenism.
Topics: Adult; Amenorrhea; Androgens; Double-Blind Method; Endocrine System Diseases; Female; Gonadotropins, | 1987 |
3 other studies available for spironolactone and Amenorrhea
| Article | Year |
|---|---|
Treatment of hirsutism with spironolactone.
Topics: Amenorrhea; Androgen Antagonists; Androgens; Androstenedione; Cytochrome P-450 Enzyme Inhibitors; Fa | 1982 |
Primary and secondary amenorrhea associated with spironolactone therapy in chronic liver disease.
Topics: Adolescent; Adult; Amenorrhea; Cholestasis; Chronic Disease; Female; Humans; Hypertension, Portal; H | 1992 |
Spironolactone therapy and amenorrhea.
Topics: Adult; Amenorrhea; Female; Humans; Kidney Diseases; Menstruation Disturbances; Spironolactone | 1970 |