spironolactone has been researched along with Allergy, Drug in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Despite the universal inclusion of asparaginase in such treatment protocols, debate on the optimal formulation and dosage of these agents continues." | 2.47 | L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. ( Baruchel, A; Boos, J; Goekbuget, N; Hunger, SP; Pieters, R; Pui, CH; Rizzari, C; Schrappe, M; Silverman, L, 2011) |
| "The drug allergy was thus the occasion for the persisting pigment deposition with circumscribed spotty pigmentation of the skin." | 1.27 | [Pigmented exanthema after spironolactone allergy in progressive systemic scleroderma]. ( Luderschmidt, C, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pieters, R | 1 |
| Hunger, SP | 1 |
| Boos, J | 1 |
| Rizzari, C | 1 |
| Silverman, L | 1 |
| Baruchel, A | 1 |
| Goekbuget, N | 1 |
| Schrappe, M | 1 |
| Pui, CH | 1 |
| Ghislain, PD | 1 |
| Bodarwe, AD | 1 |
| Vanderdonckt, O | 1 |
| Tennstedt, D | 1 |
| Marot, L | 1 |
| Lachapelle, JM | 1 |
| Luderschmidt, C | 1 |
| Licata, AA | 1 |
| Bartter, FC | 1 |
| Cohen, LS | 1 |
| Lamey, PJ | 1 |
| Gibson, J | 1 |
| Barclay, SC | 1 |
| Miller, S | 1 |
| Schmidt, P | 1 |
2 reviews available for spironolactone and Allergy, Drug
| Article | Year |
|---|---|
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase.
Topics: Asparaginase; Drug Combinations; Drug Hypersensitivity; Drug Monitoring; Erwinia; Humans; Precursor | 2011 |
Clinical pharmacology of acetylsalicylic acid.
Topics: Absorption; Aspirin; Blood Platelets; Digestive System; Drug Combinations; Drug Hypersensitivity; He | 1976 |
5 other studies available for spironolactone and Allergy, Drug
| Article | Year |
|---|---|
Drug-induced eosinophilia and multisystemic failure with positive patch-test reaction to spironolactone: DRESS syndrome.
Topics: Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophilia; Humans; Male; Middle Aged; Patch Tests; | 2004 |
[Pigmented exanthema after spironolactone allergy in progressive systemic scleroderma].
Topics: Adult; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Pigmentation Disorders; Scleroderma, Sys | 1983 |
Spironolactone-induced gynaecomastia related to allergic reaction to "Darvon compound".
Topics: Dextropropoxyphene; Drug Hypersensitivity; Drug Interactions; Gynecomastia; Humans; Male; Middle Age | 1976 |
Grinspan's syndrome: a drug-induced phenomenon?
Topics: Aged; Aged, 80 and over; Atenolol; Bendroflumethiazide; Chlorpropamide; Diabetes Mellitus, Type 2; D | 1990 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |