spironolactone has been researched along with Alcoholic Hepatitis in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with ascites due to chronic liver disease were treated with spironolactone as the sole diuretic in doses of 300 to 600 mg daily." | 7.66 | Effectiveness of high-dose spironolactone therapy in patients with chronic liver disease and relatively refractory ascites. ( Campra, JL; Reynolds, TB, 1978) |
| "Ten patients with ascites due to chronic liver disease were treated with spironolactone as the sole diuretic in doses of 300 to 600 mg daily." | 3.66 | Effectiveness of high-dose spironolactone therapy in patients with chronic liver disease and relatively refractory ascites. ( Campra, JL; Reynolds, TB, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sabesin, SM | 1 |
| Hays, RA | 1 |
| Campra, JL | 1 |
| Reynolds, TB | 1 |
2 other studies available for spironolactone and Alcoholic Hepatitis
| Article | Year |
|---|---|
Fever, diaphoresis, and jaundice in an alcoholic.
Topics: Adult; Alcoholism; Fever; Hepatitis, Alcoholic; Humans; Hyperhidrosis; Jaundice; Male; Spironolacton | 1984 |
Effectiveness of high-dose spironolactone therapy in patients with chronic liver disease and relatively refractory ascites.
Topics: Adult; Ascites; Blood Urea Nitrogen; Creatinine; Drug Evaluation; Female; Hepatitis, Alcoholic; Huma | 1978 |