spironolactone has been researched along with Age-Related Macular Degeneration in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, M | 1 |
| Mantel, I | 1 |
| Gelize, E | 1 |
| Li, X | 1 |
| Xie, X | 1 |
| Arboleda, A | 1 |
| Seminel, M | 1 |
| Levy-Boukris, R | 1 |
| Dernigoghossian, M | 1 |
| Prunotto, A | 1 |
| Andrieu-Soler, C | 1 |
| Rivolta, C | 1 |
| Canonica, J | 1 |
| Naud, MC | 1 |
| Lechner, S | 1 |
| Farman, N | 1 |
| Bravo-Osuna, I | 1 |
| Herrero-Vanrell, R | 1 |
| Jaisser, F | 1 |
| Behar-Cohen, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biomarkers Analysis of Mineralocortoid Receptor Activation in the Serum and Ocular Fluid of Patients With Choroidal Neovascularization[NCT04439708] | 250 participants (Anticipated) | Observational | 2020-06-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for spironolactone and Age-Related Macular Degeneration
| Article | Year |
|---|---|
Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Choroid; Choroidal Neovascularization; Dr | 2019 |