spironolactone has been researched along with Adenoma, Adrenal Cortical in 22 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of primary aldosteronism is presented in which the CT scan was initially misleading, adrenocortical scintigraphy was rendered inaccurate by pharmacological interference of spironolactone, and selective adrenal venous sampling of aldosterone was technically difficult." | 7.69 | Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism. ( Freitas, JE; Grekin, R; Gross, MD; Shapiro, B, 1994) |
| "Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia." | 5.35 | An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009) |
| "A case of primary aldosteronism is presented in which the CT scan was initially misleading, adrenocortical scintigraphy was rendered inaccurate by pharmacological interference of spironolactone, and selective adrenal venous sampling of aldosterone was technically difficult." | 3.69 | Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism. ( Freitas, JE; Grekin, R; Gross, MD; Shapiro, B, 1994) |
| "The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension." | 2.49 | Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism. ( Weiner, ID, 2013) |
| "Primary hyperaldosteronism (PHA) is characterized by an increased Aldosterone synthesis which is independent of the Renin-Angiotensin-Aldosterone-System (RAAS)." | 2.48 | [Primay hyperaldosteronism--diagnostic and treatment]. ( Beuschlein, F; Potthoff, SA; Vonend, O, 2012) |
| "The prevalence of primary hyperaldosteronism is 5-10% of all hypertensive patients, and clearly above the estimated prevalence in the past." | 2.43 | [Modern pharmacological aspects of hyperaldosteronism therapy]. ( Quinkler, M; Reincke, M, 2006) |
| "Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia." | 1.35 | An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Mandal, C | 1 |
| Dutta, PK | 1 |
| Weiner, ID | 1 |
| Petramala, L | 1 |
| Savoriti, C | 1 |
| Zinnamosca, L | 1 |
| Marinelli, C | 1 |
| Settevendemmie, A | 1 |
| Calvieri, C | 1 |
| Catani, M | 1 |
| Letizia, C | 1 |
| Riester, A | 1 |
| Reincke, M | 3 |
| Beuschlein, F | 2 |
| Wu, CH | 1 |
| Yang, YW | 1 |
| Hung, SC | 1 |
| Tsai, YC | 1 |
| Hu, YH | 1 |
| Lin, YH | 1 |
| Chu, TS | 1 |
| Wu, KD | 1 |
| Wu, VC | 1 |
| Karagüzel, G | 1 |
| Bahat, E | 1 |
| Imamoğlu, M | 1 |
| Ahmetoğlu, A | 1 |
| Yildiz, K | 1 |
| Okten, A | 1 |
| Katayama, A | 1 |
| Otsuka, F | 1 |
| Tanabe, K | 1 |
| Tsukamoto, N | 1 |
| Yamanaka, R | 1 |
| Matsumoto, Y | 1 |
| Nasu, Y | 1 |
| Makino, H | 1 |
| Fikri Benbrahim, O | 1 |
| García Agudo, R | 1 |
| Cazalla Cadenas, F | 1 |
| Martínez Calero, A | 1 |
| González-Spínola, J | 1 |
| Krysiak, R | 1 |
| Okopien, B | 1 |
| Cabassi, A | 1 |
| Rocco, R | 1 |
| Berretta, R | 1 |
| Regolisti, G | 1 |
| Bacchi-Modena, A | 1 |
| Potthoff, SA | 1 |
| Vonend, O | 1 |
| Stephany, JD | 1 |
| Pearl, GS | 1 |
| GADRAT, J | 1 |
| DELAUDE, A | 1 |
| JORDA, MF | 1 |
| MOREAU, G | 1 |
| CAVELL, B | 1 |
| HOEKFELT, B | 1 |
| Satoh, F | 1 |
| Ito, S | 1 |
| Quinkler, M | 1 |
| Koga, Y | 1 |
| Ohe, K | 1 |
| Gondo, S | 1 |
| Watanabe, T | 1 |
| Sakamoto, R | 1 |
| Nomura, M | 1 |
| Okabe, T | 1 |
| Kawazoe, N | 1 |
| Sasano, K | 1 |
| Yanase, T | 1 |
| Mir, FA | 1 |
| Brown, MJ | 1 |
| Appleton, DS | 1 |
| Hofmockel, G | 1 |
| Heimbach, D | 1 |
| Bussen, D | 1 |
| Frohmüller, HG | 1 |
| Shapiro, B | 1 |
| Grekin, R | 1 |
| Gross, MD | 1 |
| Freitas, JE | 1 |
| Rossi, E | 1 |
| Sani, C | 1 |
| Perazzoli, F | 1 |
| Casoli, MC | 1 |
| Negro, A | 1 |
| Dotti, C | 1 |
| Ganguly, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Postoperative Cardiovascular Index Change of Primary Aldosteronism[NCT00746070] | 300 participants (Actual) | Observational | 2007-01-31 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for spironolactone and Adenoma, Adrenal Cortical
| Article | Year |
|---|---|
Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Eplerenone; Humans; Hy | 2013 |
[Primary hyperaldosteronism: boundaries of diagnostics and therapy].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hyperfunction; Aldos | 2014 |
[Primay hyperaldosteronism--diagnostic and treatment].
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; A | 2012 |
[Adrenocortical adenoma].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Androgens; Biomarkers; | 2006 |
[Modern pharmacological aspects of hyperaldosteronism therapy].
Topics: Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocortical Adenoma; Angiotensin II Type 1 Recept | 2006 |
Primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hype | 1998 |
1 trial available for spironolactone and Adenoma, Adrenal Cortical
| Article | Year |
|---|---|
Effect of Treatment on Body Fluid in Patients with Unilateral Aldosterone Producing Adenoma: Adrenalectomy versus Spironolactone.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Aged, 80 and over; Aldosteron | 2015 |
15 other studies available for spironolactone and Adenoma, Adrenal Cortical
| Article | Year |
|---|---|
Unique Case of Cardiomyopathy Secondary to Adrenal Adenoma (Primary-Aldosteronism).
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cardiomyopathies; Female; Humans; Hyperaldosteronism; | 2023 |
Primary aldosteronism with concurrent primary hyperparathyroidism in a patient with arrhythmic disorders.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Arrhythmias, Cardiac; Electr | 2013 |
An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldoste | 2009 |
Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Angiomyolipoma; Antihyperten | 2011 |
[Diagnosis of secondary hypertension causing miscarriage during the first trimester of pregnancy].
Topics: Abortion, Spontaneous; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Antihypertensive Age | 2011 |
The effect of treatment on monocyte and lymphocyte cytokine release in patients with aldosteronoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; | 2012 |
Eplerenone use in primary aldosteronism during pregnancy.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Eplerenone; Female; Follow-U | 2012 |
Pathologic quiz case: an adrenal mass in a 54-year-old man.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Humans; Inclusion Bodies; Male; Middle Aged; Spiro | 2003 |
[Conn's syndrome with adrenocortical adenoma. Action of spirolactone, SC-9420].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diuretics; Humans; Hy | 1962 |
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL ADENOMA IN A THREE-YEAR-OLD CHILD.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Adenoma; | 1964 |
[MEN type I presenting hypokalemia and hypertension, complicated with acromegaly, adrenal cortical tumor and rectal carcinoid tumor].
Topics: Acromegaly; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Carcinoid Tumor; Female; Growt | 2006 |
Lessons in the diagnosis and management of Conn's syndrome.
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Amiloride; Amlodipine; Calcium Channel Blockers; | 2007 |
[Surgical interventions of the adrenal gland. Diagnosis and results of treatment].
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; | 1994 |
Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism.
Topics: Adosterol; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Dexamethasone; Humans; Hyperaldosteroni | 1994 |
Alterations of calcium metabolism and of parathyroid function in primary aldosteronism, and their reversal by spironolactone or by surgical removal of aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Analysis | 1995 |