spironolactone has been researched along with Adenocarcinoma in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemcitabine mono-therapy was carried out in an unresectable pancreatic cancer." | 5.33 | [A case of pancreatic cancer complicated by gemcitabine-induced peripheral edema]. ( Hirata, N; Ishiguro, A; Munakata, M; Sakata, Y; Shitara, K; Wada, R; Yabu, K, 2005) |
| "Gemcitabine mono-therapy was carried out in an unresectable pancreatic cancer." | 1.33 | [A case of pancreatic cancer complicated by gemcitabine-induced peripheral edema]. ( Hirata, N; Ishiguro, A; Munakata, M; Sakata, Y; Shitara, K; Wada, R; Yabu, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sundar, S | 1 |
| Dickinson, PD | 1 |
| Shitara, K | 1 |
| Ishiguro, A | 1 |
| Munakata, M | 1 |
| Sakata, Y | 1 |
| Hirata, N | 1 |
| Yabu, K | 1 |
| Wada, R | 1 |
| Davies, PG | 1 |
| Bare, RL | 1 |
| Torti, FM | 1 |
| Moertel, CG | 1 |
| Engstrom, P | 1 |
| Lavin, PT | 1 |
| Gelber, RD | 1 |
| Carbone, PP | 1 |
| Newmark, SR | 1 |
| Dluhy, RG | 1 |
| Bennett, AH | 1 |
1 review available for spironolactone and Adenocarcinoma
| Article | Year |
|---|---|
Endocrine therapy of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Antineoplasti | 1998 |
1 trial available for spironolactone and Adenocarcinoma
| Article | Year |
|---|---|
Chemotherapy of gastric and pancreatic carcinoma: a controlled evaluation of combinations of 5-fluorouracil with nitrosoureas and "lactones".
Topics: Adenocarcinoma; Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; N | 1979 |
4 other studies available for spironolactone and Adenocarcinoma
| Article | Year |
|---|---|
Spironolactone, a possible selective androgen receptor modulator, should be used with caution in patients with metastatic carcinoma of the prostate.
Topics: Adenocarcinoma; Aged, 80 and over; Contraindications; Heart Failure; Humans; Male; Prostate-Specific | 2012 |
[A case of pancreatic cancer complicated by gemcitabine-induced peripheral edema].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Deoxycytidine; Diuretics; Drug Administration Sched | 2005 |
Spontaneous resolution of adenocarcinoma.
Topics: Adenocarcinoma; Aged; Female; Humans; Metoclopramide; Spironolactone; Stomach Neoplasms | 1984 |
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco | 1973 |