spironolactone has been researched along with Acute Lymphoid Leukemia in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Despite the universal inclusion of asparaginase in such treatment protocols, debate on the optimal formulation and dosage of these agents continues." | 2.47 | L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. ( Baruchel, A; Boos, J; Goekbuget, N; Hunger, SP; Pieters, R; Pui, CH; Rizzari, C; Schrappe, M; Silverman, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pieters, R | 1 |
| Hunger, SP | 1 |
| Boos, J | 1 |
| Rizzari, C | 1 |
| Silverman, L | 1 |
| Baruchel, A | 1 |
| Goekbuget, N | 1 |
| Schrappe, M | 1 |
| Pui, CH | 1 |
1 review available for spironolactone and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase.
Topics: Asparaginase; Drug Combinations; Drug Hypersensitivity; Drug Monitoring; Erwinia; Humans; Precursor | 2011 |