spironolactone has been researched along with Acidosis, Renal Tubular, Type I in 8 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors describe a case of type 4 renal tubular acidosis, observed in a subject with liver cirrhosis, the pathogenetic cause of which was probably the assumption of spironolactone." | 1.30 | [Type 4 renal tubular acidosis caused by spironolactone. A case report]. ( Bruno, CM; D'Amico, R; D'Angelo, G; Neri, S; Raciti, C; Urso, G, 1997) |
| "Spironolactone therapy is a well-known cause of hyperkalaemia, but in susceptible patient, it may also be associated with metabolic acidosis." | 1.29 | Type IV renal tubular acidosis and spironolactone therapy in the elderly. ( Colledge, NR; O'Connell, JE, 1993) |
| "The complications to renal tubular acidosis such as hypokalemic muscle paralysis or chronic muscle weakness, nephrolithiasis, and osteomalacia can be avoided if the diagnosis of renal tubular acidosis is made and corrective alkali therapy is maintained." | 1.27 | Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis. ( Christensen, KS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gill, JR | 1 |
| Bell, NH | 1 |
| Bartter, FC | 1 |
| O'Connell, JE | 1 |
| Colledge, NR | 1 |
| Bruno, CM | 1 |
| Neri, S | 1 |
| D'Angelo, G | 1 |
| D'Amico, R | 1 |
| Raciti, C | 1 |
| Urso, G | 1 |
| Bravo Mata, M | 1 |
| Alonso Martín, A | 1 |
| Fuster Siebert, M | 1 |
| Paz Fernández, M | 1 |
| Cocho de Juan, J | 1 |
| Radó, J | 1 |
| Csabuda, M | 1 |
| Obana, M | 1 |
| Higashi, F | 1 |
| Kato, E | 1 |
| Christensen, KS | 1 |
| Riecker, G | 1 |
1 review available for spironolactone and Acidosis, Renal Tubular, Type I
| Article | Year |
|---|---|
[Drug-induced renal tubular acidosis].
Topics: Acetazolamide; Acidosis, Renal Tubular; Amphotericin B; Animals; Cadmium; Heparin; Humans; Indometha | 1985 |
1 trial available for spironolactone and Acidosis, Renal Tubular, Type I
| Article | Year |
|---|---|
Extrarenal effects of diuretic agents.
Topics: Acidosis, Renal Tubular; Adipose Tissue; Alkalosis; Animals; Antihypertensive Agents; Blood Volume; | 1970 |
6 other studies available for spironolactone and Acidosis, Renal Tubular, Type I
| Article | Year |
|---|---|
Impaired conservation of sodium and potassium in renal tubular acidosis and its correction by buffer anions.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Adolescent; Adult; Aldosterone; Bicarbonates; Body W | 1967 |
Type IV renal tubular acidosis and spironolactone therapy in the elderly.
Topics: Acidosis, Renal Tubular; Aged; Aged, 80 and over; Female; Humans; Hyperkalemia; Spironolactone | 1993 |
[Type 4 renal tubular acidosis caused by spironolactone. A case report].
Topics: Acidosis, Renal Tubular; Aged; Diuretics; Female; Humans; Spironolactone | 1997 |
[Gitelman's tubulopathy: deficit of K/Mg transfer].
Topics: Acidosis, Renal Tubular; Child; Humans; Hypokalemia; Magnesium; Male; Metabolism, Inborn Errors; Pot | 1992 |
[A successfully treated case of spironolactone-induced hyperkalemic quadriplegia].
Topics: Acidosis, Renal Tubular; Aged; Bicarbonates; Calcium Gluconate; Female; Humans; Hyperkalemia; Inject | 1985 |
Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Bicarbonates; Female; Humans; Hypokalemia; Middle Aged; Paralysis; Potassiu | 1985 |