spirapril and Asthma

spirapril has been researched along with Asthma* in 1 studies

Trials

1 trial(s) available for spirapril and Asthma

ArticleYear
Angiotensin-converting enzyme inhibitors in patients with bronchial responsiveness and asthma.
    Chest, 1992, Volume: 101, Issue:4

    Twenty-one subjects with known bronchial hyperreactivity were prospectively randomized in double-blind fashion to receive one of two angiotensin-converting enzyme inhibitors (ACE-I), enalapril or spirapril, for three weeks. Spirometry and methacholine provocation were performed prior to, during, and following ACE-I usage. Three of 21 subjects developed a nonproductive cough. However, only one subject wheezed slightly. Spirometry and bronchial reactivity (PD20) were unchanged throughout the study.

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cough; Double-Blind Method; Drug Tolerance; Enalapril; Female; Humans; Male; Methacholine Chloride; Middle Aged; Prospective Studies; Single-Blind Method

1992