spiperone has been researched along with Migraine Disorders in 6 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "No relationship of Kd with type of migraine, presence of vomiting, family history, frequency of attack, duration of illness and menstrual migraine was observed." | 1.35 | Platelet dopamine: D2 receptor binding in patients with migraine. ( Khanna, VK; Sankhwar, ML; Shukla, R; Vinod, P; Yadav, RS, 2009) |
| "The interactions of antimigraine agents with serotonin (5-hydroxytryptamine, 5-HT) receptor subtypes were analyzed in human frontal cortex membranes." | 1.27 | Antimigraine drug interactions with serotonin receptor subtypes in human brain. ( Peroutka, SJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glen, RC | 1 |
| Martin, GR | 1 |
| Hill, AP | 1 |
| Hyde, RM | 1 |
| Woollard, PM | 1 |
| Salmon, JA | 1 |
| Buckingham, J | 1 |
| Robertson, AD | 1 |
| Shukla, R | 1 |
| Khanna, VK | 1 |
| Vinod, P | 1 |
| Sankhwar, ML | 1 |
| Yadav, RS | 1 |
| Srikiatkhachorn, A | 2 |
| Anthony, M | 1 |
| Harrington, MA | 1 |
| Zhong, P | 1 |
| Garlow, SJ | 1 |
| Ciaranello, RD | 1 |
| Govitrapong, P | 1 |
| Limthavon, C | 1 |
| Peroutka, SJ | 1 |
1 review available for spiperone and Migraine Disorders
| Article | Year |
|---|---|
Molecular biology of serotonin receptors.
Topics: Anxiety Disorders; Humans; Migraine Disorders; Models, Molecular; Molecular Structure; Receptors, Se | 1992 |
5 other studies available for spiperone and Migraine Disorders
| Article | Year |
|---|---|
Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties.
Topics: Animals; Aorta; Computer-Aided Design; Drug Design; Haplorhini; In Vitro Techniques; Migraine Disord | 1995 |
Platelet dopamine: D2 receptor binding in patients with migraine.
Topics: Adult; Blood Platelets; Dopamine; Dopamine Antagonists; Female; Humans; Male; Migraine Disorders; Ra | 2009 |
Serotonin receptor adaptation in patients with analgesic-induced headache.
Topics: Adolescent; Adult; Aged; Analgesics; Blood Platelets; Female; Headache; Humans; Ketanserin; Male; Mi | 1996 |
5-HT2 serotonin receptor on blood platelet of migraine patients.
Topics: Adult; Blood Platelets; Electronic Data Processing; Female; Humans; Male; Migraine Disorders; Platel | 1992 |
Antimigraine drug interactions with serotonin receptor subtypes in human brain.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Binding, Competitive; Calcium Channel Blockers; Female; Fr | 1988 |