Page last updated: 2024-11-04

spiperone and Hypothermia

spiperone has been researched along with Hypothermia in 3 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"0 mg/kg, ip) hypothermia was reversed by the central and peripheral administration of the D2 antagonists S-(-)-sulpiride (3."3.68Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. ( Michel, AD; Nunes, JL; Sharif, NA; Whiting, RL, 1991)
" Concurrent lithium treatment also facilitated the degree of analgesic tolerance, and naloxone-induced withdrawal hypothermia."3.67Chronically administered morphine increases dopamine receptor sensitivity in mice. ( Martin, JR; Takemori, AE, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lai, H1
Kazi, MS1
Carino, MA1
Horita, A1
Nunes, JL1
Sharif, NA1
Michel, AD1
Whiting, RL1
Martin, JR1
Takemori, AE1

Other Studies

3 other studies available for spiperone and Hypothermia

ArticleYear
Chronic haloperidol treatment potentiates apomorphine- and ethanol-induced hypothermia in the rat.
    Life sciences, 1982, Mar-08, Volume: 30, Issue:10

    Topics: Animals; Apomorphine; Binding Sites; Corpus Striatum; Drug Synergism; Ethanol; Haloperidol; Humans;

1982
Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists.
    Neurochemical research, 1991, Volume: 16, Issue:10

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Temperature

1991
Chronically administered morphine increases dopamine receptor sensitivity in mice.
    European journal of pharmacology, 1986, Feb-18, Volume: 121, Issue:2

    Topics: Analgesia; Animals; Apomorphine; Behavior, Animal; Binding Sites; Brain; Drug Implants; Drug Toleran

1986