spiperone has been researched along with Hyperactivity, Motor in 6 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The SNAP-25 deficient mouse mutant coloboma (Cm/+) is an animal model for investigating the biochemical basis of locomotor hyperactivity." | 1.31 | Expression of catecholaminergic mRNAs in the hyperactive mouse mutant coloboma. ( Hess, EJ; Jones, MD; Williams, ME, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Köhler, C | 2 |
| Ogren, SO | 3 |
| Fuxe, K | 1 |
| Haglund, L | 1 |
| Angeby, T | 1 |
| Xu, M | 1 |
| Hu, XT | 1 |
| Cooper, DC | 1 |
| Moratalla, R | 1 |
| Graybiel, AM | 1 |
| White, FJ | 1 |
| Tonegawa, S | 1 |
| Kameda, K | 1 |
| Miura, J | 1 |
| Suzuki, K | 1 |
| Kusumi, I | 1 |
| Tanaka, T | 1 |
| Koyama, T | 1 |
| Jones, MD | 1 |
| Williams, ME | 1 |
| Hess, EJ | 1 |
| de Paulis, T | 1 |
| Kumar, Y | 1 |
| Johansson, L | 1 |
| Rämsby, S | 1 |
| Florvall, L | 1 |
| Hall, H | 1 |
| Angeby-Möller, K | 1 |
6 other studies available for spiperone and Hyperactivity, Motor
| Article | Year |
|---|---|
Studies on the mechanism of action of substituted benzamide drugs.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Brain; Catalepsy; Corpus Striatum; Humans; H | 1984 |
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Halope | 1981 |
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Electric Conductivity; Hyperkinesis; Male; Mice; Mice, | 1994 |
Effects of lithium on dopamine D2 receptor expression in the rat brain striatum.
Topics: Animals; Antidepressive Agents; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Interactions; | 2001 |
Expression of catecholaminergic mRNAs in the hyperactive mouse mutant coloboma.
Topics: Animals; Benzazepines; Catecholamines; Coloboma; Corpus Striatum; Dopamine Antagonists; Dopamine Pla | 2001 |
Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
Topics: Animals; Apomorphine; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonis | 1985 |