spiperone has been researched along with Eye Cancer, Retinoblastoma in 4 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the release of melatonin and the production of its precursors, 5-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells." | 7.68 | Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. ( Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ, 1991) |
| "We studied the release of melatonin and the production of its precursors, 5-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells." | 3.68 | Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. ( Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ, 1991) |
| " In membranes prepared from the WERI 27 human retinoblastoma cell line, specific receptor binding of the D2 antagonists [3H]methylspiperone and [125I]NAPS was observed." | 3.67 | Identification and characterization of D1 and D2 dopamine receptors in cultured neuroblastoma and retinoblastoma clonal cell lines. ( Brassard, DL; Monsma, FJ; Sibley, DR, 1989) |
| " The dopamine dose-response curve for inducing desensitization exhibits an EC50 of approximately 2-3 microM and a maximal response at approximately 0." | 1.28 | Agonist-induced desensitization of D2 dopamine receptors in human Y-79 retinoblastoma cells. ( Barton, AC; Black, LE; Sibley, DR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barton, AC | 2 |
| Black, LE | 1 |
| Sibley, DR | 3 |
| Deng, MH | 1 |
| Lopez G-Coviella, I | 1 |
| Lynch, HJ | 1 |
| Wurtman, RJ | 1 |
| Monsma, FJ | 2 |
| Brassard, DL | 1 |
4 other studies available for spiperone and Eye Cancer, Retinoblastoma
| Article | Year |
|---|---|
Agonist-induced desensitization of D2 dopamine receptors in human Y-79 retinoblastoma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Cell Differentiation; Dopamine; Dopamine Agent | 1991 |
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Butyrates; Butyric Acid; Cell Line; Colforsin; Dopamine; | 1991 |
Expression of functional D2 dopamine receptors following differentiation of Y-79 human retinoblastoma cells.
Topics: Adenylyl Cyclase Inhibitors; Binding, Competitive; Cell Membrane; Colforsin; Dopamine; Dopamine Agen | 1990 |
Identification and characterization of D1 and D2 dopamine receptors in cultured neuroblastoma and retinoblastoma clonal cell lines.
Topics: Animals; Benzazepines; Binding, Competitive; Cell Line; Dopamine Antagonists; Humans; Mice; Neurobla | 1989 |