spiperone has been researched along with Dystonia in 4 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In isolated focal dystonia, whole putaminal binding of dopamine D2-like receptor radioligands is quantitatively decreased, but it has not been known whether selected parts of the putamen are differentially affected depending upon the body part affected by dystonia." | 1.40 | Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia. ( Black, KJ; Mink, JW; Moerlein, SM; Perlmutter, JS; Revilla, FJ; Snyder, AZ; Tolia, VN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Black, KJ | 3 |
| Snyder, AZ | 1 |
| Mink, JW | 1 |
| Tolia, VN | 1 |
| Revilla, FJ | 1 |
| Moerlein, SM | 3 |
| Perlmutter, JS | 3 |
| Stambuk, MK | 2 |
| Markham, J | 2 |
| McGee-Minnich, L | 2 |
| Jankovic, J | 2 |
| Leenders, KL | 1 |
| Quinn, N | 1 |
| Frackowiak, RS | 1 |
| Marsden, CD | 1 |
4 other studies available for spiperone and Dystonia
| Article | Year |
|---|---|
Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia.
Topics: Adult; Aged; Dystonia; Female; Fluorine Radioisotopes; Hand; Humans; Magnetic Resonance Imaging; Mal | 2014 |
Decreased [18F]spiperone binding in putamen in idiopathic focal dystonia.
Topics: Adult; Aged; Basal Ganglia; Blepharospasm; Cerebrovascular Circulation; Dopamine; Dystonia; Facial M | 1997 |
Decreased [18F]spiperone binding in putamen in dystonia.
Topics: Adult; Aged; Dystonia; Female; Fluorine Radioisotopes; Handwriting; Humans; Kinetics; Male; Middle A | 1998 |
Brain dopaminergic system studied in patients with dystonia using positron emission tomography.
Topics: Adult; Brain; Dopamine; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Sp | 1988 |