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spiperone and Drug Hypersensitivity

spiperone has been researched along with Drug Hypersensitivity in 1 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"When spiperone was given subcutaneously at a dose of 30 or 150 mg/kg, 1 h after challenge with oxazolone, cutaneous contact hypersensitivity to this hapten was significantly diminished."1.28Inhibition of cutaneous contact hypersensitivity in the mouse with systemic or topical spiperone: topical application of spiperone produces local immunosuppression without inducing systemic neuroleptic effects. ( Arndt, KA; Chandrasekar, A; Galli, SJ; Sharpe, RJ; Wang, ZS, 1992)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharpe, RJ1
Chandrasekar, A1
Arndt, KA1
Wang, ZS1
Galli, SJ1

Other Studies

1 other study available for spiperone and Drug Hypersensitivity

ArticleYear
Inhibition of cutaneous contact hypersensitivity in the mouse with systemic or topical spiperone: topical application of spiperone produces local immunosuppression without inducing systemic neuroleptic effects.
    The Journal of investigative dermatology, 1992, Volume: 99, Issue:5

    Topics: Administration, Topical; Animals; Dermatitis, Contact; Dopamine Antagonists; Drug Hypersensitivity;

1992