spiperone and Depression, Involutional studies

spiperone and Depression, Involutional

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

Excerpt	Relevance	Reference
"Fluvoxamine treatment significantly improved clinical symptoms and modified [(18)F]FESP binding in the frontal and occipital cortex of all of the nine patients who completed the study; in these regions a mean 31% increase in the in vivo [(18)F]FESP binding was found (P < 0."	2.69	Effects of fluvoxamine treatment on the in vivo binding of [F-18]FESP in drug naive depressed patients: a PET study. ( Bonfanti, A; Colombo, C; Del Sole, A; Fazio, F; Galli, L; Gobbo, C; Lucca, A; Lucignani, G; Messa, C; Moresco, RM; Smeraldi, E, 2000)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (100.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Messa, C	2
Colombo, C	2
Moresco, RM	2
Gobbo, C	2
Galli, L	2
Lucignani, G	2
Gilardi, MC	1
Rizzo, G	1
Smeraldi, E	2
Zanardi, R	1
Artigas, F	1
Fazio, F	2
Bonfanti, A	1
Del Sole, A	1
Lucca, A	1

Studies

Messa, C

Colombo, C

Moresco, RM

Gobbo, C

Galli, L

Lucignani, G

Gilardi, MC

Rizzo, G

Smeraldi, E

Zanardi, R

Artigas, F

Fazio, F

Bonfanti, A

Del Sole, A

Lucca, A

Trials

1 trial available for spiperone and Depression, Involutional

Article	Year
Effects of fluvoxamine treatment on the in vivo binding of [F-18]FESP in drug naive depressed patients: a PET study. NeuroImage, 2000, Volume: 12, Issue:4 Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Depressive Disorder, Major; Female; Fluorine	2000

Article

Year

Effects of fluvoxamine treatment on the in vivo binding of [F-18]FESP in drug naive depressed patients: a PET study.

NeuroImage, 2000, Volume: 12, Issue:4

Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Depressive Disorder, Major; Female; Fluorine

2000

Other Studies

1 other study available for spiperone and Depression, Involutional

Article	Year
5-HT(2A) receptor binding is reduced in drug-naive and unchanged in SSRI-responder depressed patients compared to healthy controls: a PET study. Psychopharmacology, 2003, Volume: 167, Issue:1 Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Case-Control Studies; Depressive Disorder, M	2003

Article

Year

5-HT(2A) receptor binding is reduced in drug-naive and unchanged in SSRI-responder depressed patients compared to healthy controls: a PET study.

Psychopharmacology, 2003, Volume: 167, Issue:1

Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Case-Control Studies; Depressive Disorder, M

2003