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spiperone and Delayed Effects, Prenatal Exposure

spiperone has been researched along with Delayed Effects, Prenatal Exposure in 13 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
" The dopaminergic turnover was measured by 3,4-dihyroxyphenilacetic acid content and 3H-Spiperone binding has been carried out to determine dopaminergic receptor alterations induced by chronic ethanol consumption during pregnancy."3.66Effects of ethanol, given during pregnancy, on the offspring dopaminergic system. ( Covelli, V; Lucchi, L; Petkov, VV; Spano, PF; Trabucchi, M, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's4 (30.77)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lucchi, L2
Covelli, V1
Petkov, VV1
Spano, PF2
Trabucchi, M2
Madsen, JR1
Campbell, A1
Baldessarini, RJ1
Benson, KA1
Ali, SF2
Wilson, MC1
Peris, J1
Coleman-Hardee, M1
Millard, WJ1
Schmidt, MH1
Lee, T1
Scalzo, FM1
Frambes, NA1
Spear, LP1
Fung, YK2
Reed, JA1
Lau, YS2
Peters, DA2
Govoni, S1
Missale, C1
Memo, M1
Takagi, S1
Alleva, FR1
Seth, PK1
Balazs, T1
De Ceballos, ML1
Benedi, A1
De Felipe, C1
Del Rio, J1

Other Studies

13 other studies available for spiperone and Delayed Effects, Prenatal Exposure

ArticleYear
Effects of ethanol, given during pregnancy, on the offspring dopaminergic system.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Ethanol; Fema

1983
Effects of prenatal treatment of rats with haloperidol due to altered drug distribution in neonatal brain.
    Neuropharmacology, 1981, Volume: 20, Issue:10

    Topics: Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Brain; Female; Haloperidol; Humans; Kineti

1981
The effects of prenatal cocaine exposure on dopaminergic challenge and receptor binding in Wistar rats.
    Annals of the New York Academy of Sciences, 1996, Oct-31, Volume: 801

    Topics: Animals; Avoidance Learning; Benzazepines; Cocaine; Dopamine; Dopamine Agonists; Female; Male; Motor

1996
Cocaine in utero enhances the behavioral response to cocaine in adult rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Cocaine; Corpus Striatum; Female; Male; Motor Activity; Nucleus Accumbens; Pre

1992
Investigation of striatal dopamine D2 receptor acquisition following prenatal neuroleptic exposure.
    Psychiatry research, 1991, Volume: 36, Issue:3

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Dr

1991
Weanling rats exposed prenatally to cocaine exhibit an increase in striatal D2 dopamine binding associated with an increase in ligand affinity.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:2

    Topics: Animals; Benzazepines; Cocaine; Corpus Striatum; Female; Nucleus Accumbens; Pregnancy; Prenatal Expo

1990
Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats.
    General pharmacology, 1989, Volume: 20, Issue:5

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Drinki

1989
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Corpus Striatum; Cotinine; Female; Gestational

1989
Effects of maternal stress during different gestational periods on the serotonergic system in adult rat offspring.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Female; Gestational Age; Male; Methoxydimethyltryptamine

1988
Prenatal stress: effect on development of rat brain serotonergic neurons.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Aging; Animals; Circadian Rhythm; Female; Kinetics; Motor Activity; Neurons; Pregnancy; Prenatal Exp

1986
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens.
    Brain research, 1986, Aug-27, Volume: 381, Issue:1

    Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Female; Haloperidol; Lead Poisoni

1986
Delayed development of reproductive functions and alteration of dopamine receptor binding in hypothalamus of rats exposed prenatally to phenytoin and phenobarbital.
    Toxicology letters, 1986, Volume: 34, Issue:1

    Topics: Animals; Female; Hypothalamus; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed

1986
Prenatal exposure of rats to antidepressants enhances agonist affinity of brain dopamine receptors and dopamine-mediated behaviour.
    European journal of pharmacology, 1985, Oct-22, Volume: 116, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Dopamine; Female; Kinetics; Motor

1985