spiperone has been researched along with Decerebrate Posturing in 6 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kynuramine was found to release cardiac catecholamines and to act as a weak partial agonist on vascular alpha-adrenoceptors." | 1.27 | Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats. ( Charlton, KG; Clarke, DE; Hamed, AT; Johnson, TD, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Theodorou, A | 1 |
| Reavill, C | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Charlton, KG | 1 |
| Johnson, TD | 1 |
| Hamed, AT | 1 |
| Clarke, DE | 1 |
| Van der Werf, JF | 1 |
| Van het Schip, F | 1 |
| Sebens, JB | 1 |
| Korf, J | 1 |
| McCrea, AE | 1 |
| Stehouwer, DJ | 1 |
| Van Hartesveldt, C | 1 |
| Skarsfeldt, T | 1 |
| Hyttel, J | 1 |
| Cohen, ML | 1 |
| Kurz, KD | 1 |
| Mason, NR | 1 |
| Fuller, RW | 1 |
| Marzoni, GP | 1 |
| Garbrecht, WL | 1 |
6 other studies available for spiperone and Decerebrate Posturing
| Article | Year |
|---|---|
Kainic acid lesions of striatum and decortication reduce specific [3H]sulpiride binding in rats, so D-2 receptors exist post-synaptically on corticostriate afferents and striatal neurons.
Topics: Animals; Binding Sites; Cerebral Cortex; Corpus Striatum; Decerebrate State; Female; Hydroxydopamine | 1981 |
Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Brain; Cerebral Cortex; Decerebrate St | 1983 |
Quantification of in vivo spiperone binding in the rat striatum after lesions produced by kainate or decortication.
Topics: Animals; Butyrophenones; Cerebral Cortex; Corpus Striatum; Decerebrate State; Hydroxydopamines; Kain | 1984 |
Dopamine D1 and D2 antagonists block L-DOPA-induced air-stepping in decerebrate neonatal rats.
Topics: Animals; Animals, Newborn; Benzazepines; Decerebrate State; Dopamine D2 Receptor Antagonists; Levodo | 1997 |
The St 587-induced flexor reflex in pithed rats: a model to evaluate central alpha 1-receptor blocking properties.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Binding, Competitive; Clonidine; Decere | 1986 |
Pharmacological activity of the isomers of LY53857, potent and selective 5-HT2 receptor antagonists.
Topics: Animals; Blood Pressure; Cerebral Cortex; Corticosterone; Decerebrate State; Ergolines; Isomerism; M | 1985 |