spiperone has been researched along with Brain Ischemia in 7 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thus, cerebral ischemia that was associated with cell loss in the striatum resulted in a selective reduction of dopamine D1 receptors and not D2 receptors." | 1.29 | Effects of cerebral ischemia on dopamine receptors in the gerbil striatum. ( Araki, T; Fujiwara, T; Itoyama, Y; Kato, H; Kogure, K; Shuto, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Rahman, SMK | 1 |
| Hussain, Z | 1 |
| Morito, K | 1 |
| Takahashi, N | 1 |
| Sikder, MM | 1 |
| Tanaka, T | 1 |
| Ohta, KI | 1 |
| Ueno, M | 1 |
| Takahashi, H | 1 |
| Yamamoto, T | 1 |
| Murakami, M | 1 |
| Uyama, T | 1 |
| Ueda, N | 1 |
| Aoki, H | 1 |
| Onodera, H | 1 |
| Yae, T | 1 |
| Jian, Z | 1 |
| Kogure, K | 2 |
| Araki, T | 1 |
| Kato, H | 1 |
| Shuto, K | 1 |
| Fujiwara, T | 1 |
| Itoyama, Y | 1 |
| Burke, RE | 3 |
| Reches, A | 1 |
| Przedborski, S | 2 |
| Kostic, V | 1 |
| Jackson-Lewis, V | 2 |
| Cadet, JL | 2 |
| Kostic, VS | 1 |
| Rinne, JO | 1 |
| Säkö, E | 1 |
| Paljärvi, L | 1 |
| Mölsä, PK | 1 |
| Rinne, UK | 1 |
7 other studies available for spiperone and Brain Ischemia
| Article | Year |
|---|---|
Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A
Topics: Acyltransferases; Animals; Brain Ischemia; Disease Models, Animal; Glycerophospholipids; Mice; Phosp | 2022 |
Neural grafting to ischemic CA1 lesions in the rat hippocampus: an autoradiographic study.
Topics: Acetylcholinesterase; Animals; Autoradiography; Brain Ischemia; Brain Tissue Transplantation; Fetal | 1993 |
Effects of cerebral ischemia on dopamine receptors in the gerbil striatum.
Topics: Animals; Benzamides; Benzazepines; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dopamine Antago | 1996 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B | 1991 |
Effect of unilateral perinatal hypoxic-ischemic brain injury in the rat on dopamine D1 and D2 receptors and uptake sites: a quantitative autoradiographic study.
Topics: Animals; Animals, Newborn; Autoradiography; Benzazepines; Biogenic Amines; Brain Ischemia; Female; H | 1991 |
Effect of unilateral perinatal hypoxic-ischemic brain injury on striatal dopamine uptake sites and D1 and D2 receptors in adult rats.
Topics: Animals; Autoradiography; Benzazepines; Brain Ischemia; Corpus Striatum; Densitometry; Hypoxia; Imag | 1991 |
Brain dopamine D-2 receptors in senile dementia.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Brain Chemistry; Brain Ischemia; Caudate Nucleus; Dem | 1986 |