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spiperone and Body Weight

spiperone has been researched along with Body Weight in 31 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Chronic quipazine treatment had no long-term effect on body weight."7.66Effect of chronic administration of fenfluramine and quipazine on body weight gain after ovariectomy and on brain serotonin receptor binding. ( Bartness, T; Carlton, J; Rowland, N; Smith, G, 1983)
"The characteristics of dopamine receptors were studied in heart and kidney using the radiolabeled receptor assay of [3H]spiperone during the development of cardiac hypertrophy."3.68Altered renal dopamine receptors during development of cardiac hypertrophy. ( Chen, Y; Ganguly, PK; Mukherjee, K, 1992)
" Chronic quipazine treatment had no long-term effect on body weight."3.66Effect of chronic administration of fenfluramine and quipazine on body weight gain after ovariectomy and on brain serotonin receptor binding. ( Bartness, T; Carlton, J; Rowland, N; Smith, G, 1983)
"Treatment with cypermethrin was made on rats from the 10th to the 16th day after birth."1.30Influence of neonatal treatment with the pyrethroid insecticide cypermethrin on the development of dopamine receptors in the rat kidney. ( Amenta, F; Barili, P; Cantalamessa, F; Cavagna, R; Sabbatini, M; Tenore, G, 1998)
"The effects of melanotropin release-inhibiting factor, a tripeptide (Pro-Leu-Gly-NH2) derived from the hypothalamus, and its enzymatically stable analog, cyclo(Leu-Gly) on the supersensitivity of dopamine receptors in brain induced by chronic administration of haloperidol to male Sprague-Dawley rats was determined."1.27Effects of prolyl-leucyl-glycinamide and cyclo(leucyl-glycine) on the supersensitivity of dopamine receptors in brain induced by chronic administration of haloperidol to rats. ( Bhargava, HN, 1984)
" Chronic administration of sulpiride does not induce identical changes in striatal dopamine function to those caused by haloperidol."1.27Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat. ( Fleminger, S; Hall, MD; Jenner, P; Kilpatrick, G; Mann, S; Marsden, CD; Rupniak, NM, 1984)
" Catalepsy induced by acute administration of haloperidol, trifluoperazine or cis-flupenthixol was reduced by continuous chronic intake of cis-flupenthixol."1.27Alterations in different populations of striatal dopamine receptors produced by 18 months continuous administration of cis- or trans-flupenthixol to rats. ( Fleminger, S; Hall, MD; Jenner, P; Marsden, CD; Murugaiah, K; Theodorou, A, 1984)
"Buspirone is a novel anti-anxiety drug which has neither a benzodiazepine structure nor any other benzodiazepine-like properties."1.27Comparative chronic effects of buspirone or neuroleptics on rat brain dopaminergic neurotransmission. ( McMillen, BA, 1985)
"Comparison has been made of the effects on brain dopamine function of chronic administration of haloperidol or clozapine to rats for up to 12 months."1.27Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat. ( Fleminger, S; Hall, MD; Jenner, P; Kilpatrick, G; Mann, S; Marsden, CD; Rupniak, NM, 1985)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199022 (70.97)18.7374
1990's6 (19.35)18.2507
2000's1 (3.23)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, X1
Zhang, Y1
Chen, Y2
Qiu, Y1
Yu, M1
Xu, X1
Liu, X1
Liu, BF1
Zhang, L1
Zhang, G1
Thanos, PK1
Kim, R1
Delis, F1
Rocco, MJ1
Cho, J1
Volkow, ND1
Abramov, U1
Raud, S1
Kõks, S1
Innos, J1
Kurrikoff, K1
Matsui, T1
Vasar, E1
Clow, A1
Theodorou, A2
Jenner, P6
Marsden, CD6
Rupniak, N1
Hong, M2
Mansfield, S1
Fleminger, S4
Dyer, R1
Bhargava, HN1
Seth, PK2
Alleva, FR1
Balazs, T1
Staunton, DA1
Magistretti, PJ1
Shoemaker, WJ1
Bloom, FE1
Rupniak, NM2
Mann, S2
Hall, MD3
Kilpatrick, G2
Murugaiah, K1
Rowland, N1
Carlton, J1
Bartness, T1
Smith, G1
Cronin, MJ1
Koritnik, DR1
Lautin, A1
Wazer, D1
Stanley, M1
Rotorsen, J1
Gershon, S1
Beas-Zárate, C1
Ortuño-Sahagún, D1
Del Angel Meza, AR1
Feria-Velasco, A1
Cantalamessa, F1
Barili, P2
Cavagna, R1
Sabbatini, M1
Tenore, G1
Amenta, F2
Fringuelli, C1
Baldoni, E1
Mignini, F1
Zaccheo, D1
Ganguly, PK1
Mukherjee, K1
Peris, J1
Coleman-Hardee, M1
Millard, WJ1
Wolffgramm, J1
Rommelspacher, H1
Buck, E1
Nobrega, JN1
Dixon, LM1
Troncone, LR1
Barros, HT1
Kalkman, HO1
Neumann, V1
Brauner, V1
Fung, YK3
Reed, JA1
Lau, YS3
Tilson, HA1
Schwartz, RD1
Ali, SF1
McLamb, RL1
McMillen, BA1
Kilpatrick, GJ1
Saidi, NF1
Agrawal, AK1
Anand, M1
Parati, EA1
Parenti, M1
Locatelli, V1
Penalva, A1
Tamminga, C1
Müller, EE1
Paulose, CS1
Dakshinamurti, K1

Other Studies

31 other studies available for spiperone and Body Weight

ArticleYear
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Animals; Antipsychotic Agents; Body Weight; Chemistry Techniques, Synthetic; Drug Design; Ether-A-Go

2018
Effects of chronic methamphetamine on psychomotor and cognitive functions and dopamine signaling in the brain.
    Behavioural brain research, 2017, 03-01, Volume: 320

    Topics: Animals; Anxiety; Benzazepines; Body Weight; Brain; Carbon Isotopes; Central Nervous System Stimulan

2017
Targeted mutation of CCK(2) receptor gene antagonises behavioural changes induced by social isolation in female, but not in male mice.
    Behavioural brain research, 2004, Nov-05, Volume: 155, Issue:1

    Topics: Aggression; Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Body Weight; Cerebral Co

2004
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
    European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Bindi

1980
Elevation of circulating prolactin concentrations may not cause striatal dopamine receptor supersensitivity.
    European journal of pharmacology, 1983, Sep-30, Volume: 93, Issue:3-4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Body Weight; Corpus Striatum; Humans; Male; Prolactin; R

1983
Effects of prolyl-leucyl-glycinamide and cyclo(leucyl-glycine) on the supersensitivity of dopamine receptors in brain induced by chronic administration of haloperidol to rats.
    Neuropharmacology, 1984, Volume: 23, Issue:4

    Topics: Animals; Apomorphine; Body Weight; Cell Membrane; Corpus Striatum; Dipeptides; Haloperidol; In Vitro

1984
Alteration of high-affinity binding sites of neurotransmitter receptors in rats after neonatal exposure to streptomycin.
    Neurotoxicology, 1982, Volume: 3, Issue:3

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Kinetics; Rats; Rats, Inbred Strains; Rece

1982
Effects of chronic lithium treatment on dopamine receptors in the rat corpus striatum. I. Locomotor activity and behavioral supersensitivity.
    Brain research, 1982, Jan-28, Volume: 232, Issue:2

    Topics: Animals; Apomorphine; Body Weight; Chlorides; Corpus Striatum; Eating; Haloperidol; Humans; Lithium;

1982
Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat.
    Psychopharmacology, 1984, Volume: 84, Issue:4

    Topics: Acetylcholine; Animals; Apomorphine; Body Weight; Corpus Striatum; Haloperidol; Humans; Kinetics; Ma

1984
Alterations in different populations of striatal dopamine receptors produced by 18 months continuous administration of cis- or trans-flupenthixol to rats.
    Neuropharmacology, 1984, Volume: 23, Issue:6

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Body Weight; Catalepsy; Corpus Striatum; Flupenthixol; Huma

1984
Effect of chronic administration of fenfluramine and quipazine on body weight gain after ovariectomy and on brain serotonin receptor binding.
    Behavioral neuroscience, 1983, Volume: 97, Issue:3

    Topics: Animals; Appetite; Body Weight; Brain; Castration; Female; Fenfluramine; Muridae; Quinolines; Quipaz

1983
Dopamine receptors of the monkey anterior pituitary in various endocrine states.
    Endocrinology, 1983, Volume: 112, Issue:2

    Topics: Animals; Binding, Competitive; Body Weight; Female; Lactation; Macaca fascicularis; Male; Menstruati

1983
Chronic treatment with metoclopramide induces behavioral supersensitivity to apomorphine and enhances specific binding of 3H-spiroperidol to rat striata.
    Life sciences, 1980, Jul-28, Volume: 27, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Binding, Competitive; Body Weight; Butyrophenones; Corpus St

1980
Effect of a corn diet during development on [3H]-spiperone binding in the brain of rats at the perinatal stage.
    Comparative biochemistry and physiology. Part A, Physiology, 1995, Volume: 112, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Diet; Embryonic and Fetal Development; Female;

1995
Influence of neonatal treatment with the pyrethroid insecticide cypermethrin on the development of dopamine receptors in the rat kidney.
    Mechanisms of ageing and development, 1998, Jun-15, Volume: 103, Issue:2

    Topics: Animals; Animals, Newborn; Benzazepines; Body Weight; Insecticides; Kidney; Organ Size; Pyrethrins;

1998
Dopamine D2-like receptors in the kidney of spontaneously hypertensive rats: a radioligand binding assay and light microscope autoradiography study.
    Journal of autonomic pharmacology, 1998, Volume: 18, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Binding, Competitive; Blood Pressure; Body Weig

1998
Altered renal dopamine receptors during development of cardiac hypertrophy.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 1

    Topics: Animals; Aorta, Abdominal; Body Weight; Cardiomegaly; Constriction, Pathologic; Kidney; Kidney Corte

1992
Cocaine in utero enhances the behavioral response to cocaine in adult rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Cocaine; Corpus Striatum; Female; Male; Motor Activity; Nucleus Accumbens; Pre

1992
Ethanol reduces tolerance, sensitization, and up-regulation of D2-receptors after subchronic haloperidol.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Drug Toleranc

1990
Effects of chronic haloperidol on stress-induced oral behaviour in rats.
    Psychopharmacology, 1989, Volume: 98, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Corpus Striatum; Feeding Behavior; Haloperidol;

1989
Supersensitivity of atherosclerotic rabbit aorta to ergometrine is mediated by 5-HT2 receptors.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:12

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cyproheptadine; Ergonovine; In Vitro Techni

1989
Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats.
    General pharmacology, 1989, Volume: 20, Issue:5

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Drinki

1989
Colchicine administered into the area of the nucleus basalis decreases cortical nicotinic cholinergic receptors labelled by [3H]-acetylcholine.
    Neuropharmacology, 1989, Volume: 28, Issue:8

    Topics: Acetylcholine; Animals; Body Weight; Cerebral Cortex; Choline O-Acetyltransferase; Colchicine; Corpu

1989
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Corpus Striatum; Cotinine; Female; Gestational

1989
Comparative chronic effects of buspirone or neuroleptics on rat brain dopaminergic neurotransmission.
    Journal of neural transmission, 1985, Volume: 64, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Body Weight; Bus

1985
Effects of continuous administration for 12 months of amine-depleting drugs and chlorpromazine on striatal dopamine function in the rat.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Apomorphine; Body Weight; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Ind

1987
Neurotoxicity of endosulfan in young and adult rats.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Body Weight; Endosulfan; Female; Male; Methysergide; Rats; Receptors, Dopamine; Receptors,

1986
Receptor mechanisms of nicotine-induced locomotor hyperactivity in chronic nicotine-treated rats.
    European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3

    Topics: Animals; Body Weight; Corpus Striatum; Dopamine; Drinking; Eating; Male; Motor Activity; Nicotine; R

1988
Failure of chronic haloperidol to affect prolactin secretion due to acute haloperidol administration.
    Pharmacological research communications, 1985, Volume: 17, Issue:5

    Topics: Animals; Body Weight; Corpus Striatum; Haloperidol; Kinetics; Male; Pituitary Gland; Prolactin; Radi

1985
Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat.
    Biochemical pharmacology, 1985, Aug-01, Volume: 34, Issue:15

    Topics: Acetylcholine; Animals; Apomorphine; Body Weight; Clozapine; Corpus Striatum; Dibenzazepines; Halope

1985
Effect of pyridoxine deficiency in young rats on high-affinity serotonin and dopamine receptors.
    Journal of neuroscience research, 1985, Volume: 14, Issue:2

    Topics: Animals; Body Weight; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Fluphenazine; Organ Size; R

1985