spiperone has been researched along with Anesthesia in 6 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The concentrations of creatine phosphate, ATP and lactate were measured in the brain and skeletal muscle of rats under halothane anesthesia (1 to 2% in oxygen) and in animals either premedicated with haloperidol or spiperone (200 mg kg-1 and 2 mg kg-1) or treated with dantrolene (860 mg kg-1)." | 7.68 | The effect of haloperidol, spiperone and dantrolene on the concentrations of creatine phosphate, ATP and lactate in brain and skeletal muscle of the rat during halothane anesthesia. ( McLoughlin, JV; Wheatley, AM, 1991) |
| "The concentrations of creatine phosphate, ATP and lactate were measured in the brain and skeletal muscle of rats under halothane anesthesia (1 to 2% in oxygen) and in animals either premedicated with haloperidol or spiperone (200 mg kg-1 and 2 mg kg-1) or treated with dantrolene (860 mg kg-1)." | 3.68 | The effect of haloperidol, spiperone and dantrolene on the concentrations of creatine phosphate, ATP and lactate in brain and skeletal muscle of the rat during halothane anesthesia. ( McLoughlin, JV; Wheatley, AM, 1991) |
| "The prazosin pretreatment caused a fall in blood pressure associated with femoral vasodilatation, a small bradycardia and little change in cardiac, splanchnic or renal nerve activities." | 1.28 | The mechanism of the sympathoinhibitory action of urapidil: role of 5-HT1A receptors. ( Ramage, AG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ackerman, DM | 1 |
| Hieble, JP | 1 |
| Sarau, HM | 1 |
| Jain, TC | 1 |
| Perren, MJ | 1 |
| Feniuk, W | 2 |
| Humphrey, PP | 1 |
| Wheatley, AM | 1 |
| McLoughlin, JV | 1 |
| Stubbs, CM | 1 |
| Connor, HE | 1 |
| Ramage, AG | 1 |
| Doods, HN | 1 |
| Kalkman, HO | 1 |
| De Jonge, A | 1 |
| Thoolen, MJ | 1 |
| Wilffert, B | 1 |
| Timmermans, PB | 1 |
| Van Zwieten, PA | 1 |
6 other studies available for spiperone and Anesthesia
| Article | Year |
|---|---|
Pharmacological characterization of dopamine-4-O-sulfate.
Topics: Adenylyl Cyclase Inhibitors; Anesthesia; Animals; Clonidine; Dioxanes; Dogs; Dopamine; Ear; Female; | 1984 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Gangl | 1991 |
The effect of haloperidol, spiperone and dantrolene on the concentrations of creatine phosphate, ATP and lactate in brain and skeletal muscle of the rat during halothane anesthesia.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Antipsychotic Agents; Brain Chemistry; Dantrolene; Fema | 1991 |
BMY 7378 is an agonist at 5-HT1A receptors mediating hypotension and renal sympatho-inhibition in anaesthetised cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Pressure; Cats; Female; Heart Rat | 1991 |
The mechanism of the sympathoinhibitory action of urapidil: role of 5-HT1A receptors.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Clonidine; Heart; Heart Rate; Kidney; Male; Piperazines; | 1991 |
Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Binding Sites; Blood Pressure; In Vitro | 1985 |