Page last updated: 2024-11-04

spiperone and Alzheimer Disease

spiperone has been researched along with Alzheimer Disease in 4 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reisine, TD1
Yamamura, HI1
Bird, ED1
Spokes, E1
Enna, SJ1
Rinne, JO1
Säkö, E1
Paljärvi, L1
Mölsä, PK1
Rinne, UK1
Sparks, DL2
DeKosky, ST1
Markesbery, WR1

Other Studies

4 other studies available for spiperone and Alzheimer Disease

ArticleYear
Pre- and postsynaptic neurochemical alterations in Alzheimer's disease.
    Brain research, 1978, Dec-29, Volume: 159, Issue:2

    Topics: Aged; Alzheimer Disease; Caudate Nucleus; Choline O-Acetyltransferase; Dementia; Frontal Lobe; gamma

1978
Brain dopamine D-2 receptors in senile dementia.
    Journal of neural transmission, 1986, Volume: 65, Issue:1

    Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Brain Chemistry; Brain Ischemia; Caudate Nucleus; Dem

1986
Alzheimer's disease. Aminergic-cholinergic alterations in hypothalamus.
    Archives of neurology, 1988, Volume: 45, Issue:9

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Choline O-Acetyltransferase; Dopamine; Female; Humans

1988
Aging and Alzheimer's disease. Altered cortical serotonergic binding.
    Archives of neurology, 1989, Volume: 46, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cerebral Cortex; Frontal Lobe; Humans; Middle Age

1989