spiperone has been researched along with Affective Psychosis, Bipolar in 6 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using positron emission tomography and constrained analysis of the brain uptake of the radioligand N-[11C]methyl-spiperone ([11C]NMSP), we tested four questions: Were the assumptions underlying the quantitation valid? Is there an age decline of the density of D2-like dopamine receptors in drug-naive schizophrenia and bipolar illness? If so, is it different from that observed in normal aging? Are D2-like dopamine receptors elevated at any age in either drug-naive schizophrenic or psychotic bipolar illness patients? NMSP and haloperidol partition volumes and plasma protein fractions were not significantly different among patient groups and normal volunteers." | 3.69 | Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness. ( Dannals, RF; Gjedde, A; Kuhar, MJ; Meltzer, CC; Pearlson, GD; Ravert, HT; Reith, J; Tune, LE; Wong, DF; Young, LT, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ciaranello, RD | 1 |
| Boehme, RE | 1 |
| Pearlson, GD | 2 |
| Wong, DF | 4 |
| Tune, LE | 2 |
| Ross, CA | 1 |
| Chase, GA | 1 |
| Links, JM | 2 |
| Dannals, RF | 3 |
| Wilson, AA | 2 |
| Ravert, HT | 3 |
| Wagner, HN | 2 |
| Goyer, PF | 1 |
| Berridge, MS | 1 |
| Morris, ED | 1 |
| Semple, WE | 1 |
| Compton-Toth, BA | 1 |
| Schulz, SC | 1 |
| Miraldi, F | 1 |
| Meltzer, HY | 1 |
| Fartaçek, R | 1 |
| Geretsegger, C | 1 |
| Breitfuss, A | 1 |
| Ackenheil, M | 1 |
| Bondy, B | 1 |
| Young, LT | 1 |
| Meltzer, CC | 1 |
| Reith, J | 1 |
| Kuhar, MJ | 2 |
| Gjedde, A | 1 |
| Pearlson, G | 1 |
| Suneja, S | 1 |
| Bjorvvinssen, E | 1 |
6 other studies available for spiperone and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Genetic regulation of neurotransmitter enzymes and receptors: relationship to the inheritance of psychiatric disorders.
Topics: Animals; Bipolar Disorder; Brain; Dopamine; Dopamine beta-Hydroxylase; Enzymes; Female; Humans; Male | 1982 |
In vivo D2 dopamine receptor density in psychotic and nonpsychotic patients with bipolar disorder.
Topics: Adult; Bipolar Disorder; Brain; Carbon Radioisotopes; Caudate Nucleus; Female; Haloperidol; Humans; | 1995 |
PET measurement of neuroreceptor occupancy by typical and atypical neuroleptics.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Bipolar Disorder; Carbon Radioisotopes; Case-Control Stu | 1996 |
Elevated lymphocyte spiperone binding: a vulnerability factor for affective psychosis?
Topics: Adult; Affective Disorders, Psychotic; Aged; Aged, 80 and over; Bipolar Disorder; Female; Genetic Ca | 1997 |
Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.
Topics: Adult; Aged; Aging; Basal Ganglia; Bipolar Disorder; Brain Chemistry; Caudate Nucleus; Chromatograph | 1997 |
Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
Topics: Adult; Bipolar Disorder; Butyrophenones; Caudate Nucleus; Humans; Receptors, Dopamine; Schizophrenia | 1985 |