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spiperone and Adenoma

spiperone has been researched along with Adenoma in 12 studies

Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to define whether assessment of the uptake of [18F]fluoro-ethyl-spiperone (FESP) with positron emission tomography (PET) could be helpful for the differential diagnosis of pituitary adenomas and other parasellar lesions, and for establishing the appropriate therapeutic approach."7.69Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone. ( Bettinardi, V; Del Sole, A; Fazio, F; Giovanelli, M; Losa, M; Lucignani, G; Matarrese, M; Moresco, RM; Mortini, P, 1997)
"D2-dopamine (3,4-dihydroxyphenylethylamine) receptors were successfully solubilized with 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate from an estrone-induced rat pituitary adenoma."7.67Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma. ( Amlaiky, N; Beauregard, G; Bouvier, C; Caron, MG; Collu, R; Lafond, J; Potier, M, 1986)
" Because D2(High) receptors have not yet been detected in intact cells, we used [(3)H]domperidone to detect D2(High) sites in intact rat anterior pituitary adenoma culture cells."3.74Dopamine D2(High) receptors on intact cells. ( Seeman, P, 2008)
" The aim of this study was to define whether assessment of the uptake of [18F]fluoro-ethyl-spiperone (FESP) with positron emission tomography (PET) could be helpful for the differential diagnosis of pituitary adenomas and other parasellar lesions, and for establishing the appropriate therapeutic approach."3.69Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone. ( Bettinardi, V; Del Sole, A; Fazio, F; Giovanelli, M; Losa, M; Lucignani, G; Matarrese, M; Moresco, RM; Mortini, P, 1997)
"Dopamine receptors on human pituitary adenoma membranes were characterized using [3H] spiperone as the radioligand."3.67Demonstration of specific dopamine receptors on human pituitary adenomas. ( Arao, M; Kishimoto, S; Koga, M; Mori, S; Morimoto, Y; Nakao, H; Noma, K; Sato, B; Uozumi, T, 1987)
"D2-dopamine (3,4-dihydroxyphenylethylamine) receptors were successfully solubilized with 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate from an estrone-induced rat pituitary adenoma."3.67Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma. ( Amlaiky, N; Beauregard, G; Bouvier, C; Caron, MG; Collu, R; Lafond, J; Potier, M, 1986)
"Eight patients with pituitary adenoma including four non-functioning adenomas, two growth hormone (GH) secreting adenomas, one ACTH secreting adenoma and one TSH secreting adenoma and ten normal healthy volunteers were examined."1.29[Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma]. ( Inoue, Y; Momose, T; Nishikawa, J; Sasaki, Y; Teramoto, A; Watanabe, T, 1993)
"All the patients with Parkinson's disease also demonstrated symmetrical basal ganglia uptake in the late SPECT images, but it was diminished in parkinsonism and Wilson's disease."1.29Initial clinical experiences with dopamine D2 receptor imaging by means of 2'-iodospiperone and single-photon emission computed tomography. ( Fukuyama, H; Iida, Y; Iwasaki, Y; Konishi, J; Magata, Y; Saji, H; Shimatsu, A; Tsuchida, T; Yokoyama, A; Yonekura, Y, 1995)
"Bromocriptine (2."1.27Dopamine receptors in rat pituitary and estradiol-induced pituitary tumor: effect of chronic treatment with bromocriptine. ( Di Paolo, T; Falardeau, P, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seeman, P1
Cronin, MJ1
Cheung, CY1
Wilson, CB1
Jaffe, RB1
Weiner, RI1
Di Paolo, T1
Falardeau, P1
Serri, O1
Marchisio, AM1
Collu, R3
Hardy, J1
Somma, M1
Momose, T1
Teramoto, A1
Nishikawa, J1
Inoue, Y1
Watanabe, T1
Sasaki, Y1
Yonekura, Y1
Saji, H1
Iwasaki, Y1
Tsuchida, T1
Fukuyama, H1
Shimatsu, A1
Iida, Y1
Magata, Y1
Konishi, J1
Yokoyama, A1
Lucignani, G1
Losa, M1
Moresco, RM1
Del Sole, A1
Matarrese, M1
Bettinardi, V1
Mortini, P1
Giovanelli, M1
Fazio, F1
Bouvier, C2
Lagacé, G1
Potier, M2
Koga, M1
Nakao, H1
Arao, M1
Sato, B1
Noma, K1
Morimoto, Y1
Kishimoto, S1
Mori, S1
Uozumi, T1
Beauregard, G1
Lafond, J1
Amlaiky, N1
Caron, MG1
Otto, CA1
Marshall, JC1
Lloyd, RV1
Sherman, PS1
Fisher, SJ1
Valoppi, VL1
Rogers, WL1
Wieland, DM1
Israel, JM1
Jaquet, P1
Vincent, JD1

Other Studies

12 other studies available for spiperone and Adenoma

ArticleYear
Dopamine D2(High) receptors on intact cells.
    Synapse (New York, N.Y.), 2008, Volume: 62, Issue:4

    Topics: Adenoma; Animals; Binding, Competitive; Corpus Striatum; Domperidone; Dopamine Antagonists; Pituitar

2008
[3H]Spiperone binding to human anterior pituitaries and pituitary adenomas secreting prolactin, growth hormone, and adrenocorticotropic hormone.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:2

    Topics: Acromegaly; Adenoma; Adrenocorticotropic Hormone; Breast Neoplasms; Butyrophenones; Female; Growth H

1980
Dopamine receptors in rat pituitary and estradiol-induced pituitary tumor: effect of chronic treatment with bromocriptine.
    Biochemical and biophysical research communications, 1984, Aug-30, Volume: 123, Issue:1

    Topics: Adenoma; Animals; Bromocriptine; Estradiol; Female; Kinetics; Organ Size; Pituitary Gland, Anterior;

1984
Dopaminergic binding sites in human pituitary adenomas other than prolactinomas.
    Hormone research, 1984, Volume: 19, Issue:2

    Topics: Adenoma; Adult; Aged; Dopamine; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Neoplas

1984
[Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma].
    Kaku igaku. The Japanese journal of nuclear medicine, 1993, Volume: 30, Issue:6

    Topics: Adenoma; Adult; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Pituitary Neoplasms; Prolac

1993
Initial clinical experiences with dopamine D2 receptor imaging by means of 2'-iodospiperone and single-photon emission computed tomography.
    Annals of nuclear medicine, 1995, Volume: 9, Issue:3

    Topics: Adenoma; Basal Ganglia; Brain; Frontal Lobe; Hepatolenticular Degeneration; Humans; Iodine Radioisot

1995
Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:9

    Topics: Adenoma; Adolescent; Aged; Craniopharyngioma; Diagnosis, Differential; Female; Fluorine Radioisotope

1997
Structural differences between dopamine D2 receptors present in a rat pituitary adenoma and in transplantable rat pituitary tumors 7315a and MtTW15.
    Journal of neurochemistry, 1990, Volume: 54, Issue:3

    Topics: Adenoma; Animals; Apomorphine; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry

1990
Demonstration of specific dopamine receptors on human pituitary adenomas.
    Acta endocrinologica, 1987, Volume: 114, Issue:4

    Topics: Adenoma; Adult; Bromocriptine; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Neoplasm

1987
Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Adenoma; Affinity Labels; Animals; Cholic Acids; Electrophoresis, Polyacrylamide Gel; Estrone; Femal

1986
Use of DES-treated rats as an animal model for assessment of pituitary adenoma imaging agents.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986, Volume: 13, Issue:5

    Topics: Adenoma; Animals; Diethylstilbestrol; Female; Male; Neoplasms, Experimental; Pituitary Gland; Pituit

1986
The electrical properties of isolated human prolactin-secreting adenoma cells and their modification by dopamine.
    Endocrinology, 1985, Volume: 117, Issue:4

    Topics: Adenoma; Bromocriptine; Domperidone; Dopamine; Dose-Response Relationship, Drug; Electrophysiology;

1985