spiperone has been researched along with Adenoma in 12 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Adenoma: A benign epithelial tumor with a glandular organization.
Excerpt | Relevance | Reference |
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" The aim of this study was to define whether assessment of the uptake of [18F]fluoro-ethyl-spiperone (FESP) with positron emission tomography (PET) could be helpful for the differential diagnosis of pituitary adenomas and other parasellar lesions, and for establishing the appropriate therapeutic approach." | 7.69 | Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone. ( Bettinardi, V; Del Sole, A; Fazio, F; Giovanelli, M; Losa, M; Lucignani, G; Matarrese, M; Moresco, RM; Mortini, P, 1997) |
"D2-dopamine (3,4-dihydroxyphenylethylamine) receptors were successfully solubilized with 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate from an estrone-induced rat pituitary adenoma." | 7.67 | Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma. ( Amlaiky, N; Beauregard, G; Bouvier, C; Caron, MG; Collu, R; Lafond, J; Potier, M, 1986) |
" Because D2(High) receptors have not yet been detected in intact cells, we used [(3)H]domperidone to detect D2(High) sites in intact rat anterior pituitary adenoma culture cells." | 3.74 | Dopamine D2(High) receptors on intact cells. ( Seeman, P, 2008) |
" The aim of this study was to define whether assessment of the uptake of [18F]fluoro-ethyl-spiperone (FESP) with positron emission tomography (PET) could be helpful for the differential diagnosis of pituitary adenomas and other parasellar lesions, and for establishing the appropriate therapeutic approach." | 3.69 | Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone. ( Bettinardi, V; Del Sole, A; Fazio, F; Giovanelli, M; Losa, M; Lucignani, G; Matarrese, M; Moresco, RM; Mortini, P, 1997) |
"Dopamine receptors on human pituitary adenoma membranes were characterized using [3H] spiperone as the radioligand." | 3.67 | Demonstration of specific dopamine receptors on human pituitary adenomas. ( Arao, M; Kishimoto, S; Koga, M; Mori, S; Morimoto, Y; Nakao, H; Noma, K; Sato, B; Uozumi, T, 1987) |
"D2-dopamine (3,4-dihydroxyphenylethylamine) receptors were successfully solubilized with 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate from an estrone-induced rat pituitary adenoma." | 3.67 | Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma. ( Amlaiky, N; Beauregard, G; Bouvier, C; Caron, MG; Collu, R; Lafond, J; Potier, M, 1986) |
"Eight patients with pituitary adenoma including four non-functioning adenomas, two growth hormone (GH) secreting adenomas, one ACTH secreting adenoma and one TSH secreting adenoma and ten normal healthy volunteers were examined." | 1.29 | [Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma]. ( Inoue, Y; Momose, T; Nishikawa, J; Sasaki, Y; Teramoto, A; Watanabe, T, 1993) |
"All the patients with Parkinson's disease also demonstrated symmetrical basal ganglia uptake in the late SPECT images, but it was diminished in parkinsonism and Wilson's disease." | 1.29 | Initial clinical experiences with dopamine D2 receptor imaging by means of 2'-iodospiperone and single-photon emission computed tomography. ( Fukuyama, H; Iida, Y; Iwasaki, Y; Konishi, J; Magata, Y; Saji, H; Shimatsu, A; Tsuchida, T; Yokoyama, A; Yonekura, Y, 1995) |
"Bromocriptine (2." | 1.27 | Dopamine receptors in rat pituitary and estradiol-induced pituitary tumor: effect of chronic treatment with bromocriptine. ( Di Paolo, T; Falardeau, P, 1984) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 7 (58.33) | 18.7374 |
1990's | 4 (33.33) | 18.2507 |
2000's | 1 (8.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Seeman, P | 1 |
Cronin, MJ | 1 |
Cheung, CY | 1 |
Wilson, CB | 1 |
Jaffe, RB | 1 |
Weiner, RI | 1 |
Di Paolo, T | 1 |
Falardeau, P | 1 |
Serri, O | 1 |
Marchisio, AM | 1 |
Collu, R | 3 |
Hardy, J | 1 |
Somma, M | 1 |
Momose, T | 1 |
Teramoto, A | 1 |
Nishikawa, J | 1 |
Inoue, Y | 1 |
Watanabe, T | 1 |
Sasaki, Y | 1 |
Yonekura, Y | 1 |
Saji, H | 1 |
Iwasaki, Y | 1 |
Tsuchida, T | 1 |
Fukuyama, H | 1 |
Shimatsu, A | 1 |
Iida, Y | 1 |
Magata, Y | 1 |
Konishi, J | 1 |
Yokoyama, A | 1 |
Lucignani, G | 1 |
Losa, M | 1 |
Moresco, RM | 1 |
Del Sole, A | 1 |
Matarrese, M | 1 |
Bettinardi, V | 1 |
Mortini, P | 1 |
Giovanelli, M | 1 |
Fazio, F | 1 |
Bouvier, C | 2 |
Lagacé, G | 1 |
Potier, M | 2 |
Koga, M | 1 |
Nakao, H | 1 |
Arao, M | 1 |
Sato, B | 1 |
Noma, K | 1 |
Morimoto, Y | 1 |
Kishimoto, S | 1 |
Mori, S | 1 |
Uozumi, T | 1 |
Beauregard, G | 1 |
Lafond, J | 1 |
Amlaiky, N | 1 |
Caron, MG | 1 |
Otto, CA | 1 |
Marshall, JC | 1 |
Lloyd, RV | 1 |
Sherman, PS | 1 |
Fisher, SJ | 1 |
Valoppi, VL | 1 |
Rogers, WL | 1 |
Wieland, DM | 1 |
Israel, JM | 1 |
Jaquet, P | 1 |
Vincent, JD | 1 |
12 other studies available for spiperone and Adenoma
Article | Year |
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Dopamine D2(High) receptors on intact cells.
Topics: Adenoma; Animals; Binding, Competitive; Corpus Striatum; Domperidone; Dopamine Antagonists; Pituitar | 2008 |
[3H]Spiperone binding to human anterior pituitaries and pituitary adenomas secreting prolactin, growth hormone, and adrenocorticotropic hormone.
Topics: Acromegaly; Adenoma; Adrenocorticotropic Hormone; Breast Neoplasms; Butyrophenones; Female; Growth H | 1980 |
Dopamine receptors in rat pituitary and estradiol-induced pituitary tumor: effect of chronic treatment with bromocriptine.
Topics: Adenoma; Animals; Bromocriptine; Estradiol; Female; Kinetics; Organ Size; Pituitary Gland, Anterior; | 1984 |
Dopaminergic binding sites in human pituitary adenomas other than prolactinomas.
Topics: Adenoma; Adult; Aged; Dopamine; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Neoplas | 1984 |
[Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma].
Topics: Adenoma; Adult; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Pituitary Neoplasms; Prolac | 1993 |
Initial clinical experiences with dopamine D2 receptor imaging by means of 2'-iodospiperone and single-photon emission computed tomography.
Topics: Adenoma; Basal Ganglia; Brain; Frontal Lobe; Hepatolenticular Degeneration; Humans; Iodine Radioisot | 1995 |
Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone.
Topics: Adenoma; Adolescent; Aged; Craniopharyngioma; Diagnosis, Differential; Female; Fluorine Radioisotope | 1997 |
Structural differences between dopamine D2 receptors present in a rat pituitary adenoma and in transplantable rat pituitary tumors 7315a and MtTW15.
Topics: Adenoma; Animals; Apomorphine; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry | 1990 |
Demonstration of specific dopamine receptors on human pituitary adenomas.
Topics: Adenoma; Adult; Bromocriptine; Female; Growth Hormone; Humans; Male; Middle Aged; Pituitary Neoplasm | 1987 |
Solubilization and characterization of D2-dopamine receptors in an estrone-induced, prolactin-secreting rat pituitary adenoma.
Topics: Adenoma; Affinity Labels; Animals; Cholic Acids; Electrophoresis, Polyacrylamide Gel; Estrone; Femal | 1986 |
Use of DES-treated rats as an animal model for assessment of pituitary adenoma imaging agents.
Topics: Adenoma; Animals; Diethylstilbestrol; Female; Male; Neoplasms, Experimental; Pituitary Gland; Pituit | 1986 |
The electrical properties of isolated human prolactin-secreting adenoma cells and their modification by dopamine.
Topics: Adenoma; Bromocriptine; Domperidone; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; | 1985 |