spiperone has been researched along with Acute Disease in 3 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The binding of a D2 receptor ligand, [3H]spiperone, was measured in striatal membranes derived from rats in which acute hepatic failure induced with thioacetamide (TAA) was associated with symptoms of hepatic encephalopathy (HE), and during recovery from HE." | 3.71 | Reversible decrease of dopamine D2 receptor density in the striatum of rats with acute hepatic failure. ( Albrecht, J; Freśko, I; Lenkiewicz, A; Waśkiewicz, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sulkowski, G | 1 |
| Dabrowska-Bouta, B | 1 |
| Waśkiewicz, J | 2 |
| Rafałowska, U | 1 |
| Freśko, I | 1 |
| Lenkiewicz, A | 1 |
| Albrecht, J | 1 |
| Bondy, B | 1 |
| Ackenheil, M | 1 |
| Elbers, R | 1 |
| Fröhler, M | 1 |
3 other studies available for spiperone and Acute Disease
| Article | Year |
|---|---|
Inhibition of dopamine transport and binding of [3H] spiperone to dopamine D2 receptor by acute Pb-toxicity in vivo.
Topics: Acute Disease; Animals; Binding, Competitive; Biological Transport; Brain; Dopamine; Dopamine Antago | 1999 |
Reversible decrease of dopamine D2 receptor density in the striatum of rats with acute hepatic failure.
Topics: Acute Disease; Animals; Corpus Striatum; Dopamine Antagonists; Down-Regulation; Hepatic Encephalopat | 2001 |
Binding of 3H-spiperone to human lymphocytes: a biological marker in schizophrenia?
Topics: Acute Disease; Adult; B-Lymphocytes; Binding Sites; Butaclamol; Butyrophenones; Female; Humans; Lymp | 1985 |