spiperone has been researched along with Absence Seizure in 9 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Injection of ferric chloride (FC) into the left amygdala of rats produced limbic seizures that lasted at least 3 weeks." | 7.67 | Dopaminergic supersensitivity follows ferric chloride-induced limbic seizures. ( Bonnet, KA; Csernansky, CA; Csernansky, JG; Hollister, LE, 1985) |
| " The pharmacological tests were L-5-hydroxytryptophan syndrome in mice and tryptamine-induced clonic seizures in rats." | 3.67 | Zetidoline, a specific dopamine antagonist devoid of antiserotonergic activity in rodent brain. ( Barone, D; Peruzzi, M; Pugnetti, P; Restelli, A, 1985) |
| "Injection of ferric chloride (FC) into the left amygdala of rats produced limbic seizures that lasted at least 3 weeks." | 3.67 | Dopaminergic supersensitivity follows ferric chloride-induced limbic seizures. ( Bonnet, KA; Csernansky, CA; Csernansky, JG; Hollister, LE, 1985) |
| "The slowed rate of seizure development was not significant if the kindling stimuli were initiated 6 days posthaloperidol treatment nor if 10-mg doses of haloperidol were used for 30 days." | 1.27 | Effects of haloperidol-induced dopamine receptor supersensitivity on kindled seizure development. ( Gee, KW; Hollinger, MA; Killam, EK, 1983) |
| "Limbic seizures developed in rats following daily electrical stimulation of the basolateral nucleus of the amygdala." | 1.27 | Mesolimbic dopaminergic supersensitivity following electrical kindling of the amygdala. ( Beauclair, L; Csernansky, JG; Lombrozo, L; Mellentin, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silbergeld, EK | 1 |
| Peroutka, SJ | 1 |
| Snyder, SH | 1 |
| Gee, KW | 1 |
| Killam, EK | 1 |
| Hollinger, MA | 1 |
| Leysen, JE | 1 |
| Niemegeers, CJ | 1 |
| Tollenaere, JP | 1 |
| Laduron, PM | 1 |
| Pugnetti, P | 1 |
| Barone, D | 1 |
| Peruzzi, M | 1 |
| Restelli, A | 1 |
| Yamazaki, M | 1 |
| Suzuki, S | 1 |
| Csernansky, JG | 2 |
| Mellentin, J | 1 |
| Beauclair, L | 1 |
| Lombrozo, L | 1 |
| Gulati, A | 1 |
| Srimal, RC | 1 |
| Dhawan, KN | 1 |
| Dhawan, BN | 1 |
| Csernansky, CA | 1 |
| Bonnet, KA | 1 |
| Hollister, LE | 1 |
1 review available for spiperone and Absence Seizure
| Article | Year |
|---|---|
Multiple serotonin receptors and their physiological significance.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Humans; Lysergic Acid Diethylamide; Recepto | 1983 |
8 other studies available for spiperone and Absence Seizure
| Article | Year |
|---|---|
Indirectly acting neurotoxins.
Topics: Aminolevulinic Acid; Animals; Brain; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Lead Pois | 1983 |
Effects of haloperidol-induced dopamine receptor supersensitivity on kindled seizure development.
Topics: Amygdala; Animals; Bromocriptine; Dose-Response Relationship, Drug; Haloperidol; Kindling, Neurologi | 1983 |
Serotonergic component of neuroleptic receptors.
Topics: Animals; Apomorphine; Binding, Competitive; Corpus Striatum; Frontal Lobe; Haloperidol; Humans; In V | 1978 |
Zetidoline, a specific dopamine antagonist devoid of antiserotonergic activity in rodent brain.
Topics: 5-Hydroxytryptophan; Animals; Antipsychotic Agents; Binding, Competitive; Brain; Chlorpromazine; Dop | 1985 |
Toxicology of tremorgenic mycotoxins, fumitremorgin A and B.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Chlorpromazine; Dose-Response Relationship, Drug; G | 1986 |
Mesolimbic dopaminergic supersensitivity following electrical kindling of the amygdala.
Topics: Amygdala; Animals; Apomorphine; Electric Stimulation; Kindling, Neurologic; Limbic System; Male; Nuc | 1988 |
On the mechanism of potentiation of apomorphine-induced stereotypy due to electroconvulsive shock.
Topics: Animals; Apomorphine; Blood-Brain Barrier; Corpus Striatum; Dopamine; Electroshock; Male; Rats; Rece | 1987 |
Dopaminergic supersensitivity follows ferric chloride-induced limbic seizures.
Topics: Aggression; Amygdala; Animals; Apomorphine; Behavior, Animal; Chlorides; Ferric Compounds; Humans; I | 1985 |