sphingosine-kinase and Lymphoma--Mantle-Cell

sphingosine-kinase has been researched along with Lymphoma--Mantle-Cell* in 1 studies

Other Studies

1 other study(ies) available for sphingosine-kinase and Lymphoma--Mantle-Cell

Article	Year
Sphingosine Kinase Blockade Leads to Increased Natural Killer T Cell Responses to Mantle Cell Lymphoma. Cells, 2020, 04-21, Volume: 9, Issue:4 Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin's lymphoma. Despite being responsive to combination chemotherapy, median survival remains around 5 years due to high rates of relapse. Sphingolipid metabolism regulates MCL survival and proliferation and we found that sphingosine-1-phosphate (S1P) is upregulated in MCL cells. Therapeutic targeting of the S1P Topics: Animals; Antigens, CD1d; Cardiolipins; Cell Line, Tumor; Humans; Lymphocyte Activation; Lymphoma, Mantle-Cell; Lysophospholipids; Mice, Inbred C57BL; Natural Killer T-Cells; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine	2020

Article

Year

Sphingosine Kinase Blockade Leads to Increased Natural Killer T Cell Responses to Mantle Cell Lymphoma.

Cells, 2020, 04-21, Volume: 9, Issue:4

Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin's lymphoma. Despite being responsive to combination chemotherapy, median survival remains around 5 years due to high rates of relapse. Sphingolipid metabolism regulates MCL survival and proliferation and we found that sphingosine-1-phosphate (S1P) is upregulated in MCL cells. Therapeutic targeting of the S1P

Topics: Animals; Antigens, CD1d; Cardiolipins; Cell Line, Tumor; Humans; Lymphocyte Activation; Lymphoma, Mantle-Cell; Lysophospholipids; Mice, Inbred C57BL; Natural Killer T-Cells; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine

2020