sphingosine-kinase and Lymphoma--Mantle-Cell

sphingosine-kinase has been researched along with Lymphoma--Mantle-Cell* in 1 studies

Other Studies

1 other study(ies) available for sphingosine-kinase and Lymphoma--Mantle-Cell

ArticleYear
Sphingosine Kinase Blockade Leads to Increased Natural Killer T Cell Responses to Mantle Cell Lymphoma.
    Cells, 2020, 04-21, Volume: 9, Issue:4

    Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin's lymphoma. Despite being responsive to combination chemotherapy, median survival remains around 5 years due to high rates of relapse. Sphingolipid metabolism regulates MCL survival and proliferation and we found that sphingosine-1-phosphate (S1P) is upregulated in MCL cells. Therapeutic targeting of the S1P

    Topics: Animals; Antigens, CD1d; Cardiolipins; Cell Line, Tumor; Humans; Lymphocyte Activation; Lymphoma, Mantle-Cell; Lysophospholipids; Mice, Inbred C57BL; Natural Killer T-Cells; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine

2020