sphingosine-kinase has been researched along with Cardiomyopathies* in 1 studies
1 other study(ies) available for sphingosine-kinase and Cardiomyopathies
Article | Year |
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Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology.
Lipotoxic cardiomyopathy (LCM) is characterized by cardiac steatosis, including the accumulation of fatty acids, triglycerides and ceramides. Model systems have shown the inhibition of ceramide biosynthesis to antagonize obesity and improve insulin sensitivity. Sphingosine Δ4 desaturase (encoded by Topics: Animals; Animals, Genetically Modified; Cardiomyopathies; Cardiotoxicity; Ceramides; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Inhibitor of Apoptosis Proteins; Membrane Proteins; Mutation; Myocardial Contraction; Myocardium; Phosphotransferases (Alcohol Group Acceptor); Triglycerides | 2020 |