sphingosine-kinase and Cardiomyopathies

sphingosine-kinase has been researched along with Cardiomyopathies* in 1 studies

Other Studies

1 other study(ies) available for sphingosine-kinase and Cardiomyopathies

ArticleYear
Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology.
    Disease models & mechanisms, 2020, 08-14, Volume: 13, Issue:8

    Lipotoxic cardiomyopathy (LCM) is characterized by cardiac steatosis, including the accumulation of fatty acids, triglycerides and ceramides. Model systems have shown the inhibition of ceramide biosynthesis to antagonize obesity and improve insulin sensitivity. Sphingosine Δ4 desaturase (encoded by

    Topics: Animals; Animals, Genetically Modified; Cardiomyopathies; Cardiotoxicity; Ceramides; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Inhibitor of Apoptosis Proteins; Membrane Proteins; Mutation; Myocardial Contraction; Myocardium; Phosphotransferases (Alcohol Group Acceptor); Triglycerides

2020