sphingosine-1-phosphate has been researched along with Wet-Macular-Degeneration* in 1 studies
1 review(s) available for sphingosine-1-phosphate and Wet-Macular-Degeneration
| Article | Year |
|---|---|
Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.
Sphingosine-1-phosphate (S1P) is a pleiotropic bioactive lipid thought to be dysregulated in a variety of disease conditions. In this review, we discuss the roles of S1P in cancer and in wet age-related macular degeneration. We also explore potential treatment strategies for these disorders, including the utility of anti-S1P antibodies acting as molecular sponges to neutralize dysregulated S1P in relevant tissues. Topics: Antibodies, Monoclonal; Drug Discovery; Humans; Lysophospholipids; Molecular Targeted Therapy; Neoplasms; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Wet Macular Degeneration | 2011 |