sphingosine-1-phosphate and Tauopathies

sphingosine-1-phosphate has been researched along with Tauopathies* in 1 studies

Other Studies

1 other study(ies) available for sphingosine-1-phosphate and Tauopathies

Article	Year
Neurodegeneration Caused by S1P-Lyase Deficiency Involves Calcium-Dependent Tau Pathology and Abnormal Histone Acetylation. Cells, 2020, 09-28, Volume: 9, Issue:10 We have shown that sphingosine 1-phosphate (S1P) generated by sphingosine kinase 2 (SK2) is toxic in neurons lacking S1P-lyase (SGPL1), the enzyme that catalyzes its irreversible cleavage. Interestingly, patients harboring mutations in the gene encoding this enzyme ( Topics: Acetylation; Aldehyde-Lyases; Animals; Autophagy; Calcium; Histones; Humans; Lysophospholipids; Mice; Nerve Degeneration; Neurons; Protein Processing, Post-Translational; Sphingosine; tau Proteins; Tauopathies	2020

Article

Year

Neurodegeneration Caused by S1P-Lyase Deficiency Involves Calcium-Dependent Tau Pathology and Abnormal Histone Acetylation.

Cells, 2020, 09-28, Volume: 9, Issue:10

We have shown that sphingosine 1-phosphate (S1P) generated by sphingosine kinase 2 (SK2) is toxic in neurons lacking S1P-lyase (SGPL1), the enzyme that catalyzes its irreversible cleavage. Interestingly, patients harboring mutations in the gene encoding this enzyme (

Topics: Acetylation; Aldehyde-Lyases; Animals; Autophagy; Calcium; Histones; Humans; Lysophospholipids; Mice; Nerve Degeneration; Neurons; Protein Processing, Post-Translational; Sphingosine; tau Proteins; Tauopathies

2020