Page last updated: 2024-10-20

spermine and Pregnancy

spermine has been researched along with Pregnancy in 97 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Our purpose was to test the prediction that spermine levels in IVF culture supernatants measure by rapid ELISA assay correlate with subsequent success or failure to establish a pregnancy."3.69High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer. ( Clark, DA; Craft, I; Delcros, JG, 1996)
"It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth."3.68Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes. ( Pastor-Anglada, M; Poveda, B; Soler, C; Soley, M, 1993)
" The results indicate that there are 2 significant differences between the choriocarcinoma and the mole: 1) the choriocarcinoma is characterized by increased polyamine and nucleic acid levels, 2) tissues differ in their putrescine:spermidine and spermidine:spermine ratios."3.67Polyamines and nucleic acids in gestational trophoblastic tumors. ( Cecco, L; Cerra, M; Pagnano, AM; Paladini, A; Pasquinelli, R; Romano, M, 1985)
" Spermidine and spermine concentrations in fetal red blood cells decreased markedly with the progress of pregnancy."3.67Concentrations of polyamines in umbilical blood. ( Eguchi, K; Hiramatsu, Y; Sekiba, K, 1985)
"The in vivo metabolism of 14C-putrescine injected to rats before, during and after pregnancy was studied."3.66Metabolism of putrescine in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981)
"The urinary excretion of the diamines histamine, methylhistamine, putrescine and cadaverine and the polyamines spermidine and spermine was studied in rats which on the 19th day of pregnancy were subjected to various ectomizing operations."3.66On the biogenesis of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981)
" Spermidine and spermine continued to increase with pregnancy and retained a high level during 24-35 weeks of gestation, then decreased at term; putrescine, however, kept the low nonpregnant level during pregnancy and puerperium."3.66Alterations of red blood cells' polyamines during pregnancy and neonatal period. ( Eguchi, K; Hayase, R; Hiramatsu, Y; Sekiba, K; Yonezawa, M, 1981)
"01) suppresses the in-vitro uptake of 3H-thymidine--that is, synthesis of deoxyribonucleic acid--by spontaneously growing human lymphocytes in the presence of exogenous spermine, but only in concentrations with a higher polyamine oxidase activity than that found in maternal peripheral blood serum during pregnancy."3.66Polyamine-polyamine oxidase interaction: part of maternal protective mechanism against fetal rejection. ( Illei, G; Morgan, DM, 1980)
"The existence of a spermine oxidizing enzyme was established in human pregnancy serum by a radiochemical method, and a cross-sectional study of its quantitative profile between 10 and 40 weeks gestation was undertaken."3.66Polyamine oxidase activity in human pregnancy serum. ( Illei, G; Morgan, DM, 1979)
" Putrescine was not an inhibitor in the presence of foetal calf serum but became so in the presence of human pregnancy serum, possibly due to the action of diamine oxidase."3.66Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase. ( Allen, JC; Gaugas, JM; Hussain, JI; Smith, CJ; Thomas, JM, 1979)
" The urinary excretion of histamine, methylhistamine, putrescine, cadaverine, spermidine and spermine was examined before, during and after pregnancy in rats."3.66Increased formation of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S; Rosengren, E, 1978)
"The pregnancy of the rat brings about profound changes of the accumulation, biosynthesis and biodegradtion of the polyamines putrescine, spermidine and spermine in the reproductive tissues."3.65The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy. ( Guha, SK; Jänne, J, 1976)
"Preeclampsia and fetal growth restriction (FGR) are major causes of the more than 5 million perinatal and infant deaths occurring globally each year, and both are associated with placental dysfunction."1.48Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia. ( Aye, IL; Casero, RA; Charnock-Jones, DS; Constância, M; Cook, E; Dopierala, J; Gaccioli, F; Gong, S; Jenkins, BJ; Johnson, MD; Koulman, A; Smith, GC; Sovio, U; Wood, AM, 2018)
"Putrescine was the least concentrated of these substances in both milk types."1.42Polyamine profile in ovine and caprine colostrum and milk. ( Alichanidis, E; Galitsopoulou, A; Menexes, G; Michaelidou, AM, 2015)
"Obesity is associated with risks for mother and infant, and the mothers' dietary habits influence breast milk composition."1.39Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight. ( Ali, MA; Palme-Kilander, C; Strandvik, B; Yngve, A, 2013)
"Pregnancy is characterized by plasma volume expansion and renal sodium retention with loss of natriuretic response to atrial natriuretic peptide due to increased medullary phosphodiesterase-5 (PDE5)."1.36Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to a nitric oxide donor in the pregnant rat. ( Baylis, C; Humphreys, MH; Ni, XP; Sasser, JM, 2010)
"Pregnancy is associated with increases in maternal cardiac output and plasma volume and a reduction in peripheral vascular resistance."1.31Low-protein diet impairs vascular relaxation in virgin and pregnant rats. ( Anthony, F; Koumentaki, A; Poston, L; Wheeler, T, 2002)
"Spermine levels were not decreased and in some cases were actually increased during the course of alpha-difluoromethylornithine administration; assessment of total organ content of spermine or total polyamines per organ (putrescine + spermidine + spermine) indicated that the tissues were still actively increasing their net polyamine content despite continued inhibition of ODC."1.26Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. ( Barnes, GA; Bartolome, J; Lerea, L; Seidler, FJ; Slotkin, TA; Trepanier, PA; Weigel, SJ; Whitmore, WL, 1982)
"The putrescine conjugate was purified to homogeneity by column chromatography on Biogels P10 and P6 followed by ion-exchange chromatography on DEAE-Sephadex A-25."1.26Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid. ( Chan, WY; Rennert, OM; Seale, TW; Shukla, JB, 1979)
"Putrescine and spermine were elevated in the urine of women with normal pregnancies."1.26Polyamines in amniotic fluid, plasma, and urine during normal pregnancy. ( Campbell, JL; Christian, CD; Giles, HR; Russell, DH, 1978)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199061 (62.89)18.7374
1990's17 (17.53)18.2507
2000's9 (9.28)29.6817
2010's9 (9.28)24.3611
2020's1 (1.03)2.80

Authors

AuthorsStudies
Cai, J1
Soloway, AH1
Barth, RF1
Adams, DM1
Hariharan, JR1
Wyzlic, IM1
Radcliffe, K1
Aye, ILMH1
Gong, S2
Avellino, G1
Barbagallo, R1
Gaccioli, F2
Jenkins, BJ2
Koulman, A2
Murray, AJ1
Stephen Charnock-Jones, D1
Smith, GCS1
Umeda, K1
Miyara, M1
Ishida, K1
Sanoh, S1
Ohta, S1
Kotake, Y1
Sovio, U1
Aye, IL1
Dopierala, J1
Johnson, MD1
Wood, AM1
Cook, E1
Casero, RA1
Constância, M1
Charnock-Jones, DS1
Smith, GC1
Ali, MA1
Strandvik, B1
Palme-Kilander, C1
Yngve, A1
Wang, X1
Ying, W1
Dunlap, KA1
Lin, G1
Satterfield, MC1
Burghardt, RC1
Wu, G2
Bazer, FW2
Galitsopoulou, A1
Michaelidou, AM1
Menexes, G1
Alichanidis, E1
Basystyi, O1
Masuko, T1
Namiki, R1
Nemoto, Y1
Miyake, M1
Kizawa, Y1
Suzuki, T1
Kashiwagi, K1
Igarashi, K1
Kusama, T1
Sasser, JM1
Ni, XP1
Humphreys, MH1
Baylis, C1
Lefèvre, PL1
Palin, MF1
Murphy, BD1
Plaza-Zamora, J1
Sabater-Molina, M1
Rodríguez-Palmero, M1
Rivero, M1
Bosch, V1
Nadal, JM1
Zamora, S1
Larqué, E1
Hu, J1
Johnson, GA1
Spencer, TE1
Ravikumar, N1
Houlihan, DD2
Morrison, JJ2
Hyvönen, MT1
Uimari, A1
Keinänen, TA1
Heikkinen, S1
Pellinen, R1
Wahlfors, T1
Korhonen, A1
Närvänen, A1
Wahlfors, J1
Alhonen, L1
Jänne, J2
Moore, JJ1
Cardaman, RC1
Lundgren, DW1
Russell, DH4
Slotkin, TA3
Bartolome, J2
Persons, D1
Whitmore, WL3
Tadolini, B1
Cabrini, L1
Sechi, AM1
Muskiet, FA2
van den Berg, GA2
Kingma, AW2
Fremouw-Ottevangers, DC1
Halie, MR1
Fozard, JR1
Prakash, NJ1
Grove, J1
Seidler, FJ2
Trepanier, PA1
Lerea, L1
Barnes, GA1
Weigel, SJ2
Andersson, AC3
Henningsson, S3
Hiramatsu, Y2
Eguchi, K2
Yonezawa, M1
Hayase, R1
Sekiba, K2
Kleczkowska, D1
Niedbalski, W1
Zwierzchowski, L2
Morgan, DM4
Illei, G3
Vanella, A1
Di Silvestro, I1
D'Urso, G1
Avitabile, M1
Grasso, M1
Rapisarda, A1
Pinturo, R1
Sooranna, SR1
Das, I1
Packianathan, S1
Cain, CD1
Longo, LD1
Goel, R1
Mishra, OP2
Razdan, B1
Delivoria-Papadopoulos, M2
Brock, M1
Henley, CM1
Manev, RM1
Gabellini, N1
Manev, H1
Poveda, B1
Soler, C1
Soley, M1
Pastor-Anglada, M1
Clark, DA1
Delcros, JG1
Craft, I1
Sessa, A1
Perin, A1
Sola, B1
Staedel, C1
Remy, JS1
Bahr, A1
Behr, JP1
Wang, H1
Zhang, M1
Soda, K1
Sama, A1
Tracey, KJ1
Ekerhovd, E2
Brännström, M2
Delbro, D1
Norström, A2
Weidegård, B1
Perez Martinez, S1
Viggiano, M1
Franchi, AM1
Herrero, MB1
Ortiz, ME1
Gimeno, MF1
Villalón, M1
Rodriguez-Sallaberry, C1
Simmen, FA1
Simmen, RC1
Dennedy, MC1
Koumentaki, A1
Anthony, F1
Poston, L1
Wheeler, T1
Sinner, D1
Jawerbaum, A1
Pustovrh, C1
White, V1
Capobianco, E1
Gonzalez, E1
Gaugas, JM2
Curzen, P1
Allen, JC1
Smith, CJ1
Hussain, JI1
Thomas, JM1
D'Anna, M1
Seale, TW1
Chan, WY1
Shukla, JB1
Rennert, OM1
Heby, O1
Andersson, G1
Porta, R1
Servillo, L1
Abbruzzese, A1
Della Pietra, G1
Giles, HR1
Christian, CD1
Campbell, JL1
Rosengren, E1
Sturman, JA2
Gaull, GE2
Miller, J1
Michel, J1
Bercovici, B1
Argaman, M1
Sacks, T1
Guha, SK1
McAnulty, PA1
Yusuf, HK1
Dickerson, JW1
Hey, EN1
Waterlow, JC1
Thakur, AN1
Sheth, AR2
Purandare, TV1
Munshi, SR1
Rao, SS2
Marton, LJ1
Lee, PL1
Fujita, K1
Nagatsu, T1
Maruta, K2
Ito, M1
Senba, H1
Kano, K1
Oka, T4
Rock, DM1
Macdonald, RL1
Williams, K1
Hanna, JL1
Molinoff, PB1
Houen, G1
Mandella, RD1
Piacentini, M1
Sartori, C1
Beninati, S1
Bargagli, AM1
Cerù-Argento, MP1
Bartolome, JV1
Bartolome, MB1
Daltner, LA1
Evans, CJ1
Barchas, JD1
Kuhn, CM1
Schanberg, SM2
Leiderman, LJ1
Criss, WE1
Romano, M1
Cecco, L1
Cerra, M1
Pasquinelli, R1
Pagnano, AM1
Paladini, A1
Członkowska, M1
Guszkiewicz, A1
Ferrante, A1
Maxwell, GM1
Rencis, VO1
Allison, AC1
Visser, GH1
Ientile, R1
Russo, P1
Macaione, S1
Mizoguchi, Y1
Osa, T1
Grillo, MA1
Saito, H1
Casti, A1
Bacciottini, F1
Orlandini, G1
Reali, N1
Zannino, L1
Bernasconi, S1
Shorosheva, TG2
Verevkina, IV1
Ivanov, IP1
Perry, JW2
McVicker, TA2
Gunaga, CK1
Gunaga, KP1
Purandare, MC1
Hashimoto, H1
Unemoto, T1
Hayashi, M1
Hernandez, O1
Ballesteros, LM1
Mendez, D1
Rosado, A1
Sanguansermsri, J1
György, P1
Zilliken, F1
Levy, CC1
Schimpff, SC1
Hawk, IA1
Russel, DH1
Pearce, LA1
Neish, WJ2
Key, L2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of an Immediate-postpartum Support by IBCLC to Women With Obesity, on Breastfeeding Performance: A Randomized Trial.[NCT02756169]261 participants (Actual)Interventional2016-07-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for spermine and Pregnancy

ArticleYear
Polyamines on the reproductive landscape.
    Endocrine reviews, 2011, Volume: 32, Issue:5

    Topics: Animals; Embryo Implantation; Embryonic Development; Female; Fertilization; Gonadal Steroid Hormones

2011
Clinical relevance of polyamines.
    Critical reviews in clinical laboratory sciences, 1983, Volume: 18, Issue:3

    Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch

1983
Ethanol and polyamine metabolism: physiologic and pathologic implications: a review.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:2

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hist

1997
Metabolism and function of polyamines.
    The International journal of biochemistry, 1985, Volume: 17, Issue:9

    Topics: Acetyltransferases; Animals; Cell Differentiation; DNA Replication; Female; Mammary Glands, Animal;

1985

Other Studies

93 other studies available for spermine and Pregnancy

ArticleYear
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
    Journal of medicinal chemistry, 1997, Nov-21, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA

1997
Placental sex-dependent spermine synthesis regulates trophoblast gene expression through acetyl-coA metabolism and histone acetylation.
    Communications biology, 2022, 06-15, Volume: 5, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Female; Gene Expression; Histones; Humans; Male; Placenta; Polyamine

2022
Carbofuran causes neuronal vulnerability to glutamate by decreasing GluA2 protein levels in rat primary cortical neurons.
    Archives of toxicology, 2018, Volume: 92, Issue:1

    Topics: Acetylcholinesterase; Animals; Calcium; Carbofuran; Cell Membrane; Cells, Cultured; Cerebral Cortex;

2018
Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia.
    JCI insight, 2018, 07-12, Volume: 3, Issue:13

    Topics: Cell Survival; Female; Fetal Development; Fetal Growth Retardation; Gene Expression Regulation; Gene

2018
Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2013, Volume: 26 Suppl 1

    Topics: Adult; Body Mass Index; Breast Feeding; Feeding Behavior; Female; Guidelines as Topic; Humans; Lacta

2013
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
    Biology of reproduction, 2014, Volume: 90, Issue:4

    Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantatio

2014
Polyamine profile in ovine and caprine colostrum and milk.
    Food chemistry, 2015, Apr-15, Volume: 173

    Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Colostrum; Female; Goats; Milk;

2015
[POLYAMINE CONCENTRATION IN ERYTHROCYTES IN THE BLOOD OF PREGNANT WOMEN WITH INTRAUTERINE GROWTH RETARDATION].
    Georgian medical news, 2016, Issue:261

    Topics: Adult; Case-Control Studies; Erythrocytes; Female; Fetal Growth Retardation; Humans; Polyamines; Pre

2016
Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:2

    Topics: Animals; Anthraquinones; Cell Line, Tumor; Cells, Cultured; Cloning, Molecular; Dansyl Compounds; El

2009
Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to a nitric oxide donor in the pregnant rat.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:4

    Topics: Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Inhibitors; Female; Kidney

2010
Polyamines in human breast milk for preterm and term infants.
    The British journal of nutrition, 2013, Aug-28, Volume: 110, Issue:3

    Topics: Breast Feeding; Female; Humans; Infant, Newborn; Infant, Premature; Lactation; Milk, Human; Polyamin

2013
Polyamine synthesis from proline in the developing porcine placenta.
    Biology of reproduction, 2005, Volume: 72, Issue:4

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Fe

2005
Effects of polyamines on human umbilical artery tone in vitro.
    Journal of the Society for Gynecologic Investigation, 2004, Volume: 11, Issue:8

    Topics: Adult; Female; Gestational Age; Humans; In Vitro Techniques; Polyamines; Pregnancy; Spermidine; Sper

2004
Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.
    RNA (New York, N.Y.), 2006, Volume: 12, Issue:8

    Topics: Acetyltransferases; Alternative Splicing; Animals; Exons; Female; Gene Expression Regulation, Enzymo

2006
Spermine-enhanced protein phosphorylation in human placenta.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 176, Issue:3

    Topics: Adenosine Triphosphate; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Molecular Weig

1984
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
    Life sciences, 1984, Sep-03, Volume: 35, Issue:10

    Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine;

1984
Representative applications of heparin-sepharose in the removal of polyamines from biological materials.
    Applied biochemistry and biotechnology, 1984, Volume: 9, Issue:2

    Topics: Animals; Cattle; DNA; Female; Male; Membranes; Methods; Mitochondria, Heart; Polyamines; Pregnancy;

1984
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
    Clinical chemistry, 1984, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography,

1984
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
    Life sciences, 1980, Dec-08, Volume: 27, Issue:23

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone

1980
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; O

1982
Metabolism of putrescine in the pregnant rat.
    Acta physiologica Scandinavica, 1981, Volume: 113, Issue:4

    Topics: Animals; Carbon Dioxide; Female; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Sper

1981
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
    Toxicology letters, 1982, Volume: 14, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Pol

1982
On the biogenesis of diamines and polyamines in the pregnant rat.
    Acta endocrinologica, 1981, Volume: 98, Issue:3

    Topics: Animals; Cadaverine; Castration; Diamines; Female; Fetus; Histamine; Hysterectomy; Methylhistamines;

1981
Alterations of red blood cells' polyamines during pregnancy and neonatal period.
    Biology of the neonate, 1981, Volume: 40, Issue:3-4

    Topics: Cadaverine; Chromatography, High Pressure Liquid; Erythrocytes; Female; Fetal Blood; Humans; Infant,

1981
Effects of spermidine and spermine on DNA synthesis in isolated nuclei and on the activity of DNA polymerases alpha and beta from the mammary gland of pregnant rabbit.
    Acta biochimica Polonica, 1981, Volume: 28, Issue:3-4

    Topics: Animals; Cell Nucleus; DNA; DNA Polymerase I; DNA Polymerase II; Female; Mammary Glands, Animal; Pre

1981
Polyamine-polyamine oxidase interaction: part of maternal protective mechanism against fetal rejection.
    British medical journal, 1980, May-31, Volume: 280, Issue:6227

    Topics: Cell Division; Cells, Cultured; DNA; Female; Humans; Lymphocytes; Oxidoreductases Acting on CH-NH Gr

1980
Polyamine levels in rat placenta during pregnancy.
    Acta Europaea fertilitatis, 1980, Volume: 11, Issue:1

    Topics: Animals; Female; Placenta; Pregnancy; Pregnancy, Animal; Rats; Spermidine; Spermine; Time Factors

1980
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth R

1995
Ornithine decarboxylase activity and polyamine concentrations in fetal rat brain: response to chronic hypoxic-hypoxia and/or carbon monoxide-hypoxia.
    Brain research. Developmental brain research, 1994, Nov-18, Volume: 83, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Carbon Monoxide; Embryonic and Fetal Development; Female; Gestatio

1994
Modification of NMDA receptor by in vitro lipid peroxidation in fetal guinea pig brain.
    Neuroscience letters, 1993, Mar-19, Volume: 151, Issue:2

    Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; Guinea Pi

1993
Postnatal changes in cochlear polyamine metabolism in the rat.
    Hearing research, 1994, Volume: 72, Issue:1-2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cochlea; Eflornithine; Female; Organ of Corti; Orni

1994
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
    Neuroreport, 1993, Volume: 4, Issue:6

    Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinosit

1993
Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes.
    Biology of the neonate, 1993, Volume: 63, Issue:1

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Disease M

1993
High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer.
    Journal of assisted reproduction and genetics, 1996, Volume: 13, Issue:6

    Topics: Culture Media, Conditioned; Embryo Transfer; Enzyme-Linked Immunosorbent Assay; Female; Fertilizatio

1996
Lipospermine-mediated gene transfer technique into murine cultured cortical cells.
    Journal of neuroscience methods, 1997, Volume: 71, Issue:2

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Cytomegalovirus; DNA, Viral; Embryo, Mamma

1997
Fetuin protects the fetus from TNF.
    Lancet (London, England), 1997, Sep-20, Volume: 350, Issue:9081

    Topics: alpha-Fetoproteins; Animals; Female; Humans; In Vitro Techniques; Macrophages; Mice; Pregnancy; Sper

1997
Nitric oxide mediated inhibition of contractile activity in the human uterine cervix.
    Molecular human reproduction, 1998, Volume: 4, Issue:9

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Cervical Ripening; Cervix Uteri; Female; Humans; In V

1998
Nitric oxide-mediated effects on myometrial contractility at term during prelabor and labor.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:6

    Topics: Adult; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Humans; In Vitro Techniques; Labor,

1999
Effect of nitric oxide synthase inhibitors on ovum transport and oviductal smooth muscle activity in the rat oviduct.
    Journal of reproduction and fertility, 2000, Volume: 118, Issue:1

    Topics: Analysis of Variance; Animals; Cell Count; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fall

2000
Polyamine- and insulin-like growth factor-I-mediated proliferation of porcine uterine endometrial cells: a potential role for spermidine/spermine N(1)-acetyltransferase during peri-implantation.
    Biology of reproduction, 2001, Volume: 65, Issue:2

    Topics: Acetylation; Acetyltransferases; Animals; Blotting, Northern; Cell Division; DNA; Embryo Implantatio

2001
Polyamine effects on human myometrial contractility.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2002
Low-protein diet impairs vascular relaxation in virgin and pregnant rats.
    Clinical science (London, England : 1979), 2002, Volume: 102, Issue:5

    Topics: Acetylcholine; Animals; Dietary Proteins; Embryonic and Fetal Development; Female; Mesenteric Arteri

2002
Levels of endothelin-1 in embryos from control and neonatal streptozotocin-induced diabetic rats, and their relationship with nitric oxide generation.
    Reproduction, fertility, and development, 2002, Volume: 14, Issue:1-2

    Topics: Abnormalities, Multiple; Animals; Animals, Newborn; Case-Control Studies; Diabetes Mellitus, Experim

2002
Polyamine interaction with pregnancy serum in suppression of lymphocyte transformation.
    Lancet (London, England), 1978, Jan-07, Volume: 1, Issue:8054

    Topics: Animals; Female; Fetus; Humans; Immune Sera; Immunosuppression Therapy; Immunosuppressive Agents; In

1978
Polyamine oxidase activity in human pregnancy serum.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:11

    Topics: Cross-Sectional Studies; Female; Humans; Isoniazid; Male; Oxidoreductases Acting on CH-NH Group Dono

1979
Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase.
    European journal of biochemistry, 1979, Volume: 102, Issue:1

    Topics: Animals; Blood; Cattle; Culture Media; Diamines; Female; Humans; Lymphocyte Activation; Oxidoreducta

1979
[Preliminary study of the behavior of urinary polyamines in non-pregnant conditions, in pregnant women and in abortive pathology of the 1st trimester].
    Minerva ginecologica, 1979, Volume: 31, Issue:5

    Topics: Abortion, Spontaneous; Abortion, Threatened; Adult; Age Factors; Female; Humans; Polyamines; Pregnan

1979
Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid.
    Clinica chimica acta; international journal of clinical chemistry, 1979, Aug-01, Volume: 95, Issue:3

    Topics: Amino Acids; Amniotic Fluid; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Huma

1979
The distribution of polyamine oxidase activity in the fetomaternal compartments.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:11

    Topics: Cesarean Section; Decidua; Female; Fetal Blood; Fetus; Humans; Oxidoreductases Acting on CH-NH Group

1979
Simplified micro-method for the quantitative analysis of putrescine, spermidine and spermine in urine.
    Journal of chromatography, 1978, Jan-01, Volume: 145, Issue:1

    Topics: Chromatography, Thin Layer; Dansyl Compounds; Female; Humans; Microchemistry; Pregnancy; Putrescine;

1978
Automated chromatographic analysis of human placenta polyamines..
    Biochemical medicine, 1978, Volume: 19, Issue:2

    Topics: Chromatography, Gas; Female; Gestational Age; Humans; Mass Spectrometry; Placenta; Polyamines; Pregn

1978
Polyamines in amniotic fluid, plasma, and urine during normal pregnancy.
    American journal of obstetrics and gynecology, 1978, Nov-15, Volume: 132, Issue:6

    Topics: Amniotic Fluid; Female; Gestational Age; Humans; Polyamines; Pregnancy; Putrescine; Spermidine; Sper

1978
Increased formation of diamines and polyamines in the pregnant rat.
    The Journal of physiology, 1978, Volume: 285

    Topics: Animals; Cadaverine; Diamines; Female; Guanidines; Histamine; Hydrolysis; Methylhistamines; Polyamin

1978
Polyamine metabolism in the brain and liver of the developing monkey.
    Journal of neurochemistry, 1975, Volume: 25, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta;

1975
Studies on the antimicrobial activity of amniotic fluid.
    American journal of obstetrics and gynecology, 1976, May-15, Volume: 125, Issue:2

    Topics: Amniotic Fluid; Anti-Bacterial Agents; Antibiosis; Candida albicans; Enterococcus faecalis; Escheric

1976
The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy.
    Biochimica et biophysica acta, 1976, Jun-23, Volume: 437, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Animals; Female; Organ Specificity; Ornithine Decarboxylase; Ovar

1976
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
    Journal of neurochemistry, 1977, Volume: 28, Issue:6

    Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infa

1977
Antisera to gonadotrophins and placental function in mice. I. Effect on polyamine content.
    Journal of reproduction and fertility, 1975, Volume: 43, Issue:2

    Topics: Animals; Cross Reactions; DNA; Female; Immune Sera; Luteinizing Hormone; Mice; Placenta; Polyamines;

1975
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
    Clinical chemistry, 1975, Volume: 21, Issue:12

    Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema

1975
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Expe

1976
Polyamine transport and metabolism in mouse mammary gland. General properties and hormonal regulation.
    The Journal of biological chemistry, 1976, May-10, Volume: 251, Issue:9

    Topics: Animals; Biological Transport, Active; Cells, Cultured; Female; Insulin; Kinetics; Mammary Glands, A

1976
The polyamine diaminodecane (DA-10) produces a voltage-dependent flickery block of single NMDA receptor channels.
    Neuroscience letters, 1992, Sep-14, Volume: 144, Issue:1-2

    Topics: Animals; Diamines; Female; Ion Channels; Kinetics; N-Methylaspartate; Neurons; Oocytes; Polyamines;

1992
NMDA receptor modification in the fetal guinea pig brain during hypoxia.
    Neurochemical research, 1992, Volume: 17, Issue:12

    Topics: Animals; Brain; Dizocilpine Maleate; Female; Fetal Hypoxia; Glutamates; Glutamic Acid; Glycine; Guin

1992
Developmental changes in the sensitivity of the N-methyl-D-aspartate receptor to polyamines.
    Molecular pharmacology, 1991, Volume: 40, Issue:5

    Topics: Age Factors; Animals; Animals, Newborn; Cerebral Cortex; Dizocilpine Maleate; Female; Fetus; Glutama

1991
Affinity chromatographic isolation of a major polyamine binding protein from serum and placenta, identified as serum albumin.
    Journal of chromatography, 1990, Apr-27, Volume: 527, Issue:1

    Topics: Carrier Proteins; Chromatography, Affinity; Female; Humans; Placenta; Pregnancy; Serum Albumin; Sper

1990
Polyamine biosynthesis in the developing rabbit palate.
    Journal of craniofacial genetics and developmental biology, 1985, Volume: 5, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; DNA; Female; Gestational Age; Ornithine De

1985
Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy.
    The Biochemical journal, 1986, Mar-01, Volume: 234, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Animals; Female; Kidney; Liver; Ornithine Decarboxylase; Polyamin

1986
Effects of beta-endorphin on ornithine decarboxylase in tissues of developing rats: a potential role for this endogenous neuropeptide in the modulation of tissue growth.
    Life sciences, 1986, Jun-23, Volume: 38, Issue:25

    Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Endorphins; Female; Kidney; Liver; Male; Naloxone

1986
The characterization and regulation of a polyamine-responsive, cyclic nucleotide-independent protein kinase activity in the mouse mammary gland.
    Biochimica et biophysica acta, 1985, Feb-21, Volume: 844, Issue:2

    Topics: Adenosine Triphosphate; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cy

1985
Polyamines and nucleic acids in gestational trophoblastic tumors.
    Tumori, 1985, Feb-28, Volume: 71, Issue:1

    Topics: Adult; Choriocarcinoma; DNA, Neoplasm; Female; Humans; Hydatidiform Mole; Middle Aged; Polyamines; P

1985
Effect of polyamine limitation on DNA synthesis and development of mouse preimplantation embryos in vitro.
    Journal of reproduction and fertility, 1986, Volume: 76, Issue:1

    Topics: Animals; Blastocyst; Culture Media; DNA; Eflornithine; Embryonic Development; Female; In Vitro Techn

1986
Inhibition of the respiratory burst of human neutrophils by the polyamine oxidase-polyamine system.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:4

    Topics: Animals; Carbon Dioxide; Catalase; Cattle; Female; Hexosephosphates; Humans; Kinetics; Male; Neutrop

1986
Gestational-age-dependent concentrations of polyamines, their conjugates and metabolites in urine and amniotic fluid.
    British journal of obstetrics and gynaecology, 1988, Volume: 95, Issue:7

    Topics: Amniotic Fluid; Female; Gestational Age; Humans; Infant, Newborn; Polyamines; Pregnancy; Putrescine;

1988
Polyamine localization and biosynthesis in chemically fractionated rat retina.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Female; Male; Ornithine Decarboxylase; Photoreceptor Cell

1986
Effects of polyamines on the mechanical and electrical activities of the isolated circular muscle of rat uterus.
    The Japanese journal of physiology, 1985, Volume: 35, Issue:6

    Topics: Animals; Cadaverine; Electric Conductivity; Electric Stimulation; Female; In Vitro Techniques; Myome

1985
Alterations of polyamines in body fluids during pregnancy in rats.
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:2

    Topics: Animals; Body Fluids; Chromatography, High Pressure Liquid; Estradiol; Female; Polyamines; Pregnancy

1985
Pattern of human blood spermidine and spermine in prematurity.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Apr-30, Volume: 147, Issue:3

    Topics: Female; Humans; Infant, Newborn; Infant, Premature; Male; Pregnancy; Spermidine; Spermine

1985
Concentrations of polyamines in umbilical blood.
    Acta medica Okayama, 1985, Volume: 39, Issue:4

    Topics: Embryonic and Fetal Development; Erythrocytes; Erythropoiesis; Female; Fetal Blood; Fetus; Gestation

1985
[Deaminization of polyamines and other compounds by placental mitochondria in normal and complicated labor].
    Akusherstvo i ginekologiia, 1974, Volume: 0, Issue:7

    Topics: Biogenic Amines; Female; Humans; Labor, Obstetric; Mitochondria; Obstetric Labor Complications; Plac

1974
[Spermine level in the myometrium and placenta of women with late toxemia and habitual abortion in their anamnesis].
    Akusherstvo i ginekologiia, 1974, Issue:9

    Topics: Abortion, Habitual; Adolescent; Adult; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Spermine;

1974
Spermidine as a possible mediator of glucocorticoid effect on milk protein synthesis in mouse mammary epithelium in vitro.
    The Journal of biological chemistry, 1974, Dec-10, Volume: 249, Issue:23

    Topics: Aldosterone; Amidines; Animals; Carboxy-Lyases; Cell Differentiation; Epithelium; Female; Glyoxal; H

1974
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary G

1972
Polyamines in human placenta.
    Indian journal of biochemistry & biophysics, 1972, Volume: 9, Issue:3

    Topics: Female; Humans; Placenta; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine

1972
Inhibitory action of spermine on the contractions of rat uterus.
    The American journal of physiology, 1973, Volume: 225, Issue:3

    Topics: Animals; Calcium; Electrophysiology; Female; Muscle Contraction; Muscle, Smooth; Papaverine; Pregnan

1973
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
    Endocrinology, 1973, Volume: 92, Issue:4

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins

1973
Studies on the function of glucocorticoid in mouse mammary epithelial cell differentiation in vitro. Stimulation of glucose 6-phosphate dehydrogenase.
    The Journal of biological chemistry, 1974, Jun-10, Volume: 249, Issue:11

    Topics: Adipose Tissue; Animals; Cell Differentiation; Culture Techniques; Dose-Response Relationship, Drug;

1974
Polyamine biosynthesis in human fetal liver and brain.
    Pediatric research, 1974, Volume: 8, Issue:4

    Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liv

1974
Polyamines in human and cow's milk.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:8

    Topics: Animals; Cadaverine; Cattle; Chromatography, Thin Layer; Dansyl Compounds; Dialysis; DNA; Europe; Fe

1974
Urinary polyamines in cancer patients.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph

1971
Polyamines in the developing rat and in supportive tissues.
    Biochimica et biophysica acta, 1972, Jan-31, Volume: 259, Issue:2

    Topics: Amniotic Fluid; Animals; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Gestational Age; Histidin

1972
Histamine and spermidine content in brain during development.
    Science (New York, N.Y.), 1969, Dec-05, Volume: 166, Issue:3910

    Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Female; Fetus; Gestational Age; Histamine; Pregna

1969
Polyamines and glutathione in livers of normal rats of different ages and in livers of pregnant rats.
    Biochemical pharmacology, 1968, Volume: 17, Issue:4

    Topics: Age Factors; Amines; Animals; Female; Glutathione; Liver; Male; Neoplasm Transplantation; Pregnancy;

1968
Polyamines and glutathione in tissues of lactating rats (Rattus rattus) and in the Rd-3 adcites tumour.
    Comparative biochemistry and physiology, 1968, Volume: 27, Issue:3

    Topics: Amines; Animals; Female; Glutathione; Lactation; Liver; Mammary Glands, Animal; Pregnancy; Rats; Sar

1968