spermine has been researched along with Parkinson Disease in 4 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perni, M | 1 |
| Flagmeier, P | 1 |
| Limbocker, R | 1 |
| Cascella, R | 1 |
| Aprile, FA | 1 |
| Galvagnion, C | 1 |
| Heller, GT | 1 |
| Meisl, G | 1 |
| Chen, SW | 1 |
| Kumita, JR | 1 |
| Challa, PK | 1 |
| Kirkegaard, JB | 1 |
| Cohen, SIA | 1 |
| Mannini, B | 1 |
| Barbut, D | 1 |
| Nollen, EAA | 1 |
| Cecchi, C | 1 |
| Cremades, N | 1 |
| Knowles, TPJ | 1 |
| Chiti, F | 1 |
| Zasloff, M | 1 |
| Vendruscolo, M | 1 |
| Dobson, CM | 1 |
| Grabenauer, M | 1 |
| Bernstein, SL | 1 |
| Lee, JC | 1 |
| Wyttenbach, T | 1 |
| Dupuis, NF | 1 |
| Gray, HB | 1 |
| Winkler, JR | 1 |
| Bowers, MT | 1 |
| Gomes-Trolin, C | 1 |
| Nygren, I | 1 |
| Aquilonius, SM | 1 |
| Askmark, H | 1 |
| Antony, T | 1 |
| Hoyer, W | 1 |
| Cherny, D | 1 |
| Heim, G | 1 |
| Jovin, TM | 1 |
| Subramaniam, V | 1 |
1 trial available for spermine and Parkinson Disease
| Article | Year |
|---|---|
Increased red blood cell polyamines in ALS and Parkinson's disease.
Topics: Amyotrophic Lateral Sclerosis; Biogenic Polyamines; Erythrocytes; Female; Humans; Levodopa; Male; Mi | 2002 |
3 other studies available for spermine and Parkinson Disease
| Article | Year |
|---|---|
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Line; Cholestanes; Disease Models, Animal; Hu | 2018 |
Spermine binding to Parkinson's protein alpha-synuclein and its disease-related A30P and A53T mutants.
Topics: alpha-Synuclein; Mass Spectrometry; Mutant Proteins; Mutation; Parkinson Disease; Protein Binding; S | 2008 |
Cellular polyamines promote the aggregation of alpha-synuclein.
Topics: alpha-Synuclein; Binding Sites; Circular Dichroism; Cloning, Molecular; Escherichia coli; Humans; Mi | 2003 |