Page last updated: 2024-10-20

spermine and Mucopolysaccharidosis I

spermine has been researched along with Mucopolysaccharidosis I in 1 studies

Mucopolysaccharidosis I: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.

Research Excerpts

ExcerptRelevanceReference
"Identification of biomarkers for central nervous system disease in MPS patients would facilitate the evaluation of new agents in clinical trials."1.46Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis. ( Bell, P; Dalla Corte, A; de Souza, CFM; Giugliani, R; Hinderer, C; Katz, N; Louboutin, JP; Lund, TC; Mesaros, C; Nayal, M; Orchard, PJ; Tolar, J; Weng, L; Wilson, JM, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hinderer, C1
Katz, N1
Louboutin, JP1
Bell, P1
Tolar, J1
Orchard, PJ1
Lund, TC1
Nayal, M1
Weng, L1
Mesaros, C1
de Souza, CFM1
Dalla Corte, A1
Giugliani, R1
Wilson, JM1

Other Studies

1 other study available for spermine and Mucopolysaccharidosis I

ArticleYear
Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis.
    Human molecular genetics, 2017, 10-01, Volume: 26, Issue:19

    Topics: Adolescent; Animals; Biomarkers; Central Nervous System Diseases; Child; Disease Models, Animal; Dog

2017