spermine has been researched along with Lymphoma in 12 studies
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of mouse lymphoma L5178Y cells with spermine in Fischer's medium containing bovine serum lead to formation of chromatid aberrations." | 7.67 | Clastogenic and cytotoxic effects of spermine oxidation products in mouse lymphoma L5178Y cells. ( Bouzyk, E; Rosiek, O, 1988) |
| " This report describes a Phase Ib clinical trial investigating PG-11047 in combination with cytotoxic and anti-angiogenic chemotherapeutic agents in patients with advanced refractory metastatic solid tumors or lymphoma." | 7.01 | A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. ( Becerra, CHR; Boyd, TE; Casero, RA; Conkling, PR; Fitzgerald, M; Garbo, LE; Jotte, RM; Marton, LJ; Murray Stewart, T; Richards, DA; Smith, DA; Stephenson, JJ; Vogelzang, NJ; Von Hoff, D; Wu, HH, 2021) |
| "Treatment of mouse lymphoma L5178Y cells with spermine in Fischer's medium containing bovine serum lead to formation of chromatid aberrations." | 3.67 | Clastogenic and cytotoxic effects of spermine oxidation products in mouse lymphoma L5178Y cells. ( Bouzyk, E; Rosiek, O, 1988) |
| " This report describes a Phase Ib clinical trial investigating PG-11047 in combination with cytotoxic and anti-angiogenic chemotherapeutic agents in patients with advanced refractory metastatic solid tumors or lymphoma." | 3.01 | A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. ( Becerra, CHR; Boyd, TE; Casero, RA; Conkling, PR; Fitzgerald, M; Garbo, LE; Jotte, RM; Marton, LJ; Murray Stewart, T; Richards, DA; Smith, DA; Stephenson, JJ; Vogelzang, NJ; Von Hoff, D; Wu, HH, 2021) |
| "Erythrocytes from 24 patients with malignant lymphoma and 40 healthy controls were subjected to polyamine determination, using high-performance liquid chromatography." | 1.26 | Elevated polyamine content in erythrocytes of malignant lymphoma patients. ( Kita, K; Saeki, Y; Shirakawa, S; Uchino, H; Uehara, N, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Murray Stewart, T | 1 |
| Von Hoff, D | 1 |
| Fitzgerald, M | 1 |
| Marton, LJ | 1 |
| Becerra, CHR | 1 |
| Boyd, TE | 1 |
| Conkling, PR | 1 |
| Garbo, LE | 1 |
| Jotte, RM | 1 |
| Richards, DA | 1 |
| Smith, DA | 1 |
| Stephenson, JJ | 1 |
| Vogelzang, NJ | 1 |
| Wu, HH | 1 |
| Casero, RA | 1 |
| Russell, DH | 1 |
| Haddox, MK | 1 |
| Gehring, U | 1 |
| Muskiet, FA | 2 |
| van den Berg, GA | 1 |
| Kingma, AW | 1 |
| Fremouw-Ottevangers, DC | 2 |
| Halie, MR | 2 |
| Hospattankar, AV | 1 |
| Advani, SH | 1 |
| Vaidya, NR | 1 |
| Electricwalla, SE | 1 |
| Braganca, BM | 1 |
| Uehara, N | 1 |
| Kita, K | 1 |
| Shirakawa, S | 1 |
| Uchino, H | 1 |
| Saeki, Y | 1 |
| Stratingh, CM | 1 |
| Harrison, GS | 1 |
| Wang, Y | 1 |
| Tomczak, J | 1 |
| Hogan, C | 1 |
| Shpall, EJ | 1 |
| Curiel, TJ | 1 |
| Felgner, PL | 1 |
| Fujita, K | 1 |
| Nagatsu, T | 1 |
| Maruta, K | 1 |
| Ito, M | 1 |
| Senba, H | 1 |
| Singh, AB | 1 |
| Thomas, TJ | 1 |
| Thomas, T | 1 |
| Singh, M | 1 |
| Mann, RA | 1 |
| Yamanaka, H | 1 |
| Kubota, M | 1 |
| Carson, DA | 1 |
| Bouzyk, E | 1 |
| Rosiek, O | 1 |
| Voronchikhina, LD | 1 |
| Vorozhtsova, SI | 1 |
| Minakov, VN | 1 |
| Zinov'ev, IuV | 1 |
| Shkanakina, TP | 1 |
1 trial available for spermine and Lymphoma
| Article | Year |
|---|---|
A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cisplat | 2021 |
11 other studies available for spermine and Lymphoma
| Article | Year |
|---|---|
Effects of dexamethasone and dibutyryl cyclic AMP on polyamine synthesizing enzymes in mouse lymphoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Bucladesine; Carboxy-Lyases; Cell Line; Dexamethasone; In | 1981 |
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography, | 1984 |
Elevation of serum polyamines in malignant lymphomas and acute myeloid leukemia.
Topics: Adult; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Methods; Oxidoreductases; | 1980 |
Elevated polyamine content in erythrocytes of malignant lymphoma patients.
Topics: Adolescent; Adult; Aged; Erythrocytes; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B- | 1980 |
Mass spectrometric identification of isoputreanine, a metabolite of spermidine and/or spermine, in human urine.
Topics: Amino Acids, Diamino; Humans; Lymphoma; Mass Spectrometry; Spermidine; Spermine | 1982 |
Optimization of gene transfer using cationic lipids in cell lines and primary human CD4+ and CD34+ hematopoietic cells.
Topics: Animals; Antigens, CD34; Cations; CD4-Positive T-Lymphocytes; Cell Line; DNA; Gene Expression; Gene | 1995 |
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Expe | 1976 |
Differential effects of polyamine homologues on the prevention of DL-alpha-difluoromethylornithine-mediated inhibition of malignant cell growth and normal immune response.
Topics: Animals; Cell Division; Cell Line; Concanavalin A; Cytotoxicity, Immunologic; Eflornithine; Isomeris | 1992 |
Synergistic inhibition of polyamine synthesis and growth by difluoromethylornithine plus methylthioadenosine in methylthioadenosine phosphorylase-deficient murine lymphoma cells.
Topics: Adenosine; Animals; Cell Division; Cell Line; Deoxyadenosines; Drug Synergism; Eflornithine; Kinetic | 1987 |
Clastogenic and cytotoxic effects of spermine oxidation products in mouse lymphoma L5178Y cells.
Topics: Animals; Cell Line; Chromatids; Chromosome Aberrations; Dose-Response Relationship, Drug; Lymphoma; | 1988 |
[Significance of polyamines for the early diagnosis of spontaneous hemoblastoses in AKR mice].
Topics: Animals; Biomarkers, Tumor; Brain Chemistry; Female; Kidney; Liver; Lung; Lymphoma; Male; Mice; Mice | 1988 |